Profil Keamanan Ventilator Venindo Kode R-03 dengan Penilaian Oxygen Index (OI), Rasio PaO2/FiO2 dan Oxygen Saturation Index (OSI) Pada Pasien Paska Operasi di ICU RSUP Dr. Sardjito Yogyakarta:

Abstract

Background: Respiratory failure is a condition resulting from inadequate gas exchange in the respiratory system which is characterized by failure to transport O2 into the blood (hypoxemic type respiratory failure) or removal of carbon dioxide (CO2) from the blood (hypercapnic type respiratory failure). A ventilator is a device used to assist and replace the respiratory system in critical patients who experience respiratory failure. Mechanical ventilation can induce lung injury. The use of Oxygen Index (OI), PaO2/FiO2 ratio, Oxygen Saturation Index (OSI) can describe aspects of the severity of lung injury.

Objective: To determine the OI value, PaO2/FiO2 ratio, and OSI as markers for assessing the safety of the Venindo R-03 Ventilator in post-operative patients treated in the ICU of RSUP Dr. Sardjito.

Method: This research uses a quasi-experimental research design. The number of samples taken were post-operative patients treated in the ICU. A sample size of 38 patients was obtained and data processing could then be carried out.

Results: This research shows that the use of the Venindo ventilator code R-03 and the Hamilton ventilator code T1 does not affect  oxygenation status from the basic condition before using the ventilator as evidenced by the average OI value with both types of ventilator not being significantly different compared to the basic condition before using the ventilator (OI pre vs OI post 1 p = 0.527, OI pre vs OI post 2 p = 0.566, PF pre vs PF post 1 p = 0.199, PF pre vs PF post 2 p = 0.274, OSI pre vs OSI post 1 p = 0.600, OSI pre vs OSI post 2 p = 0.402). The average PaO2/FiO2 ratio after using the Venindo ventilator code R-03 when compared with after using the Hamilton ventilator had a statistically significant difference (PF post 1 vs PF post 2 p = 0.039) but clinically there was no difference.

Conclusion In this study, it was found that there were no significant differences in OI values, PaO2/FiO2 ratio and OSI before and after using the Venindo R-03 ventilator and the HamiltonT-1 ventilator. Meanwhile, the average PaO2/FiO2 ratio after using the Venindo ventilator code R-03 when compared with after using the Hamilton ventilator has a statistically significant difference but clinically no significant difference was found. This research also proves a strong correlation between OI and the PaO2/FiO2 ratio so that OI can have the potential to be a parameter in assessing lung injury.

Keywords: Ventilator, Oxygen Index, PaO2/FiO2 ratio, oxygen saturation index