Effect of aloe vera on the proliferation phase of oral mucosal wound healing in rats
![](/public/site/images/admin/icons/icon-doi.png)
Ameta Primasari(1*), Yendriwati Yendriwati(2), Minasari Minasari(3), Erlin Kristiani Buaya(4), Sri Ayu Winda Madani(5), Kartika Nabila Sembiring(6), Rizka Hidayati(7)
(1) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(2) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(3) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(4) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(5) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(6) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(7) Department of Oral Biology, Faculty of Dentistry, University of Sumatera Utara, North Sumatra
(*) Corresponding Author
Abstract
Keywords
Full Text:
PDFReferences
1. Nanci A. Ten Cate’s Oral Histology: Development. J Oral Maxillofac Surg. 2018;
48: 98–99.
2. Primasari A, Sinulingga ER. Differences of wound healing in the buccal part and
oral mucosa labial after giving lemongrass extracts (Cymbopogon ciratus). Int J
Homeopath Nat Med. 2019; 5(1): 36-41. doi: 10.11648/j.ijhnm.20190501.16
3. Dawson DV, Drake DR, Hill JR, Brogden KA, Fischer CL, Wertz PW. Organization, barrier
function and antimicrobial lipids of the oral mucosa. Int J Cosmet Sci. 2013; 35(3): 220–
223. doi: 10.1111/ics.12038
4. Anura A. Traumatic oral mucosal lesions: a mini review and clinical update. Oral Health
Dent Manag. 2014; 13(2): 254-259.
5. Harper D, Young A, McNaught CE. The physiology of wound healing. United
Kingdom: Elsevier Ltd; 2014. 445–450.
6. Wang PH, Huang BS, Horng HC, Yeh CC, Chen YJ. Wound healing. J Chin Med Assoc.
2018; 81(2): 94–101. doi: 10.1016/j.jcma.2017.11.002
7. Brandão LM, Reis PRM, Araujo ACV, Santos MHAS, Miguel MP. Evaluation of
wound healing treated with latex derived from rubber trees and Aloe Vera extract in
rats 1. Acta Cirúrgica Bras. 2016; 31(9): 571. doi: 10.1590/S0102-865020160090000001
8. Kumar S, Yadav JP. Ethnobotanical and pharmacological properties of Aloe vera:
A review. J Med Plants Res. 2014; 8(48): 1387–1398. doi: 10.5897/JMPR2014.5336x
9. Sujatha G, Kumar GS, Muruganandan J, Prasad TS. Aloe vera in dentistry. J Clin
Diagnostic Res. 2014; 8(10): 1. doi: 10.7860/JCDR/2014/8382.4983
10. Budiyanto MAK. Efek ekstrak lidah buaya (Aloe vera) terhadap diameter penyembuhan
luka decubbitus pada tikus putih. Malang: Universitas Muhammadiyah Malang Press;
2017. 1.
11. Listari KM, Hasanah A. Comparison of Jatropha multifida L gel and Aloe Vera
gel to the number of blood vessels post gingivectomy. Malaysian Journal of Medicine
and Health Science. 2020; 16(12): 9346.
12. Ningsih JR, Haniastuti T, Handajani J. Reepitelisasi luka soket pasca pencabutan gigi
setelah pemberian gel getah pisang raja. Jurnal Ilmu Kedokteran Gigi. 2019; 168:
198–221.
13. Hajhashemi V, Ghannadi A, Heidari AH. Antiinflammatory and wound healing activities of
Aloe littoralis in rats. Res Pharm Sci. 2012; 7(2): 73-8.
14. Mustaqim A, Asri A, Almurdi. Pengaruh pemberian gel lidah buaya (Aloe vera)
terhadap gambaran histopatologi gaster tikus wistar yang diinduksi indometasin.
Jurnal Kesehatan Andalas. 2017; 6(3): 641-646. doi: 10.25077/jka.v6i3.751
15. Nazir F, Zahari A, Anas E. Pengaruh pemberian gel lidah buaya (Aloe vera)
terhadap jarak pinggir luka pada tikus Wistar. Jurnal Kesehatan Andalas. 2015;
4(3): 827–34. 10.25077/jka.v4i3.371
16. Hobson R. Vitamin E and wound healing: An evidence-based review. Int Wound J. 2016;
13: 331–5. doi: 10.1111/iwj.12295.
17. Zinder R, Cooley R, Vlad LG, Molnar JA. Vitamin A and wound healing. Nutr Clin
Pract. 2019; 34: 839–49. doi: 10.1002/ncp.10420.
18. Teplicki E, Ma Q, Castillo DE, Zarei M, Hustad AP, Chen J, Li J. The effects of aloe
vera on wound healing in cell proliferation, migration, and viability. Wounds. 2018;
30(9): 263–268.
19. Kalangi SJR. Khasiat Aloe vera dan madu topikal pada re-epitelisasi dan pembentukan
jaringan granulasi luka eksisi kulit telinga kelinci. J Biomedik. 2014; 5(3): 171–80.
doi: 10.35790/jbm.5.3.2013.4338
20. DiPietro LA. Angiogenesis and wound repair: when enough is enough. J Leukoc Biol. 2016;
100(5): 979–984. doi: 10.1189/jlb.4MR0316-102R.
21. Ruauw EF, Wantania FE, Leman MA. Pengaruh lidah buaya (Aloe Vera) terhadap waktu
penutupan luka sayat pada mukosa rongga mulut tikus Wistar. Pharmacon. 2016; 5(2): 22–28.
![](/public/site/images/admin/icons/icon-doi.png)
Article Metrics
![](/public/site/images/admin/icons/icon-graph.png)
![](/public/site/images/admin/icons/icon-pdf.png)
Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Majalah Kedokteran Gigi Indonesia
![Creative Commons License](http://i.creativecommons.org/l/by-sa/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.