Pengaruh Medication Therapy Management terhadap Kadar HbA1c Pasien Diabetes Melitus yang Mendapatkan Terapi Insulin

Jusnita Akuba; Chairun Wiedyaningsih; Tri Murti Andayani

doi:10.22146/farmaseutik.v21i1.98974

Pengaruh Medication Therapy Management terhadap Kadar HbA1c Pasien Diabetes Melitus yang Mendapatkan Terapi Insulin

https://doi.org/10.22146/farmaseutik.v21i1.98974

Jusnita Akuba⁽¹⁾, Chairun Wiedyaningsih^(2*), Tri Murti Andayani⁽³⁾

(1) Magister Farmasi Klinik, Fakultas Farmasi Universitas Gadjah Mada Yogyakarta
(2) Universitas Gadjah Mada
(3) Departemen Farmakologi Fakultas Farmasi UGM
(*) Corresponding Author

Abstract

Pasien diabetes melitus yang mendapatkan terapi insulin rata-rata mempunyai kadar HbA1c relatif tinggi. Kurangnya pengetahuan dan kepatuhan pasien terkait terapi insulin dapat menjadi menyebab terjadinya hipoglikemia yang dapat memperburuk kondisi klinik pasien. Medication Therapy Management merupakan sebuah model intervensi apoteker berkolaborasi dengan tenaga kesehatan lainnya untuk mengatasi permasalahan terkait obat dan meningkatkan outcome pasien secara individu. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penerapan medication therapy management terhadap kadar HbA1c pasien diabetes melitus yang menggunakan terapi insulin. Penelitian ini menggunakan rancangan kuasi eksperimental dengan one group pretest-posttest design dilakukan pada 25 pasien diabetes melitus yang mendapatkan terapi insulin yang rutin berkunjung ke poliklinik RSUD Toto Kabila Gorontalo dan memenuhi kriteria inklusi. Pasien mendapatkan intervensi pelayanan berbasis medication therapy management dan dilakukan pengukuran kadar HbA1c pre dan post intervensi. Analisis perubahan kadar HbA1c pre dan post intervensi menggunakan uji paired t-test. Setelah pelayanan berbasis MTM terjadi penurunan kadar HbA1c dengan rata-rata 10,93 ± 2,22 menjadi 9,42 ± 2,54 dengan p = 0,006. Hal ini menunjukkan bahwa penerapan medication therapy management dapat menurunkan kadar HbA1c pasien diabetes melitus yang mendapatkan terapi insulin.

Keywords

medication therapy management; diabetes melitus; insulin; kadar HbA1c

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DOI: https://doi.org/10.22146/farmaseutik.v21i1.98974