Evaluation of Peptic Ulcer Medication Use in Patients with Peptic Ulcer at Inpatient Installation RSUD Sultan Syarif Mohamad Alkadrie

https://doi.org/10.22146/farmaseutik.v15i1.45261

Novi Yana Santika(1*), Rise Desnita(2), Muhammad Akib Yuswar(3)

(1) Program Studi Farmasi Fakultas Kedokteran Universitas Tanjungpura Pontianak
(2) Program Studi Farmasi Fakultas Kedokteran Universitas Tanjungpura Pontianak
(3) Program Studi Farmasi Fakultas Kedokteran Universitas Tanjungpura Pontianak
(*) Corresponding Author

Abstract


Peptic ulcer is an upper gastrointestinal tract disease caused by hypersecretion of acids and pepsin of gastric mucosa. Peptic ulcer disease can be caused by several factors such as smoking, fast food, alcoholic beverages, NSAIDs and Helycobacter pylori. The purpose of this research was to obtain the distribution of antiulcer and itsrationality on peptic ulcer inpatients at the RSUD Sultan Syarif Mohamad Alkadrie Pontianak. This study is a descriptive observational study with cross sectional design. Data from medical record collected retrospectively.  This research using medical record peptic ulcer inpatients from January to December in 2017. The samples used were 34 of 44 patients who met  the  inclusion criteria. Based on results, the distribution of anti ulcer were omeprazole (2.94%), pantoprazole (73.53%), lansoprazole (26.47%), ranitidine 5.89%, 58.82% antacids and 85.29% sucralfat. The result of rationality evaluation on criteriaof appropriate indication (100%);appropriate drug (55.88%); appropriate patient (97.06%); and appropriate (61.76%). Overall,the rationality of treatment that meets all four rational treatment criterias was 78.68%.

Keywords


Peptic ulcer, Types of Drugs and Rationality

Full Text:

PDF


References

Astuti, D.W., (2012). Pola Penggunaan Obat Tukak Peptik (Peptic ulcer Disease) Pada Pasien Geriatrik Di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2006-2010. [SKRIPSI]. Surakarta: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Sebelas Maret.

BNF. (2009). British National Formulary, Edisi 57. England: British Medical Association Royal Pharmacetical of Great Britain.

Dipiro, J.T., Talbert, R.L., Yee, G.C., Matzke, G.R., Wells, B,G., dan Posey, L.M. (2008). Pharmacotherapy A Phatophysiologic Approach, Seventh Edition: Me Graw-Hill Companies United State.

Dipiro, J.T., Wells, B.G., Schwinghammer, T.L., dan Dipiro, C.V. (2012). Pharmacotherapy Handbook Ninth Edition. Inggris: McGraw-Hill Education Companies.

Dowling, T.C. (2008). Quantification of Renal Function, Editor: Dipiro, J.T., Talbert, J.T., Yee, G.C,, Matzke, G.R., Wells, B, Posey, L.M. Pharmacotherapy A Pathophysiologic Approach, Seven Edition. USA: Mc Graw Hill Companies.

Eisner, F., dkk. (2017). Gastric Ulcer

Complications after the Introduction of Proton Pump Inhibitors into Clinical Routine: 20-Year Experience: Visceral Medicine. (33:221–226).

Nasif, H., Dahlan, R., Lingga, L.I. (2008). Jurnal Profil dan Optimalisasi Penggunaan Kombinasi Anti Tukak Dengan Antasida Pada Pasien Tukak Peptik Di Ruang Rawat Inap SMF Penyakit Dalam RSAM Bukit Tinggi. Online (http://www.ffarmasi.unand.ac.id/pub/jurnalhansen diakses 16 Juni 2016).

Rizqah., Nur’aini., dan noviyanto, F. (2016). Evaluasi Penggunaan Obat Tukak Peptik (peptic Ulcer Desease) di Rumah Sakit Bhayangkara Brimob Tahun 2015. Tanggerang: Sekolah Tinggi Muhammadiyah Tanggerang; Vol III: No.2

Sanusi, I.A. (2011). Tukak Lambung. In, A.A., Rani, M.S.K., dan Syam, A.F. Buku Ajar Gastroenterologi. Jakarta: Interna Publishing.

Saverio, dkk. (2014). Diagnosis and treatment of perforated or bleeding peptic ulcer: 2013 WSES position paper: World Journal of Emergency Surgery.

Setiawati, S., Alwi, S., Sudoyo, A.W., Simadibrata, M.K., Setiyohadi, B., dan Syam, A.F. (2015). Buku Ajar Ilmu Penyakit Dalam Jilid II Edisi VI. Jakarta: Interna Publishing.

Subramanian, A. (2009). Drugs Facts and Comparisons. (S.L Schweain, Ed): Wolters Kluwer Health. Vancouver.

Tarigan, P., (2009). Tukak Gaster. Dalam : Sudoyo, A.W., Setiyohadi, B., Alwi, I., Simadibrata, M., Setiati, S. Buku Ajar Ilmu Penyakit Dalam Edisi V Jilid 1. Jakarta : Pusat Penerbitan Ilmu Penyakit Dalam.

Truter, I. (2009). Peptic Ulcer Disease: SA Pharmaceutical journal.



DOI: https://doi.org/10.22146/farmaseutik.v15i1.45261

Article Metrics

Abstract views : 7031 | views : 110761

Refbacks

  • There are currently no refbacks.


Majalah Farmaseutik Indexed by:

   
 
Creative Commons Licence
 
 
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.