Phytochemical and Pharmacological Activities of Curcuma purpurascens Blume, A Review

https://doi.org/10.22146/jtbb.75891

Oktariani Pramiastuti(1), Subagus Wahyuono(2*), Nanang Fakhrudin(3), Puji Astuti(4)

(1) Doctoral Program of Pharmaceutical Science, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.; Pharmacy Study Program, Faculty of Health Sciences, Universitas Bhamada, Jl. Cut Nyak Dhien, Kalisapu, Slawi, 52416, Indonesia.
(2) Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.; Medicinal Plants and Natural Products Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.
(3) Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.; Medicinal Plants and Natural Products Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.
(4) Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.; Medicinal Plants and Natural Products Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Jl. Sekip Utara Yogyakarta, 55281, Indonesia.
(*) Corresponding Author

Abstract


Curcuma sp. is generally used for medicine, starch sources, preservatives, dyes and cosmetics. The use of Curcuma spp. for medical has increased because there have been many studies related to its active ingredients, such as flavonoids, essential oils, tannins, quinones, and terpenoids, as well as pharmacological activities, including wound healing, antioxidants, antifungal, anticancer, gastroprotective, and hepatoprotective. Curcuma purpurascens Blume is a species of Curcuma from family Zingiberaceae and used for traditional medicine. This article focuses on reviewing the literatures on C. purpurascens and discussing its morphology, phytochemical content, and pharmacological aspects. The method used to review this article was by exploring several databases such as Scopus, Pub Med, and Google Scholar to identify and download original articles and research journals related to the morphology, phytochemical content, and biological activity of Curcuma purpurascens Blume. The result of this review will later provide information about the uses and presence of Curcuma purpurascens Blume which is still rarely studied so further study related to its pharmacological activity tests and active compound as natural medicines can be explored.


Keywords


Curcuma purpurascens Blume, phytochemistry, pharmacology

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References

Abas, F. et al., 2005. A Labdane Diterpene Glucoside from the Rhizomes of Curcuma mangga, Journal of Natural Products, 68(7), pp.1090–1093. doi: https://doi.org/10.1021/np0500171.

Al-Reza, S. M. et al., 2010. Essential oil composition and antioxidant activities of Curcuma aromatica Salisb., Food and Chemical Toxicology, 48(6), pp.1757–1760. doi: 10.1016/j.fct.2010.04.008.

Andriyani, R. & Udin, L.Z., 2006. Aktivitas Antibakteri Temu Tis, Prosiding Seminar Nasional, IPTEK Solusi Kemandirian bangsa Dalam Tahun Indonesia untuk Ilmu Pengetahuan, 2006, Agustus 2-3, yogyakarta, pp.45–53. Available at: http://lipi.go.id/publikasi/aktivitas-antibakteri-temu-tis/10646.

Ayati, Z. et al., 2019. Ethnobotany, Phytochemistry and Traditional Uses of Curcuma spp. and Pharmacological Profile of Two Important Species (C. longa and C. zedoaria): A Review. Current Pharmaceutical Design, 25(8), pp.871–935. doi: 10.2174/1381612825666190402163

940.

Babu, K.N. et al., 2016. Protocols for In Vitro Propagation , Conservation, Synthetic Seed Production , Microrhizome Production , and Molecular Profi ling in Turmeric ( Curcuma longa L .). doi: 10.1007/978-1-4939-3332-7.

Benzie, I.F.F. & Galor, W., 2011. Herbal Medicine: Biomolecular and Clinical Aspects, 2nd edn., CRC Press/Taylor & Francis. https://pubmed.ncbi.nlm.nih.gov/22593937/

Buemi, M. et al., 2004. Recombinant human erythro_poietin stimulates angiogenesis and healing of ischemic skin wounds. SHOCK, 22(2), pp.169–173. doi: 10.1097/01.shk.0000133591.47776.bd

Chan, E.W.C et al., 2007. Antioxidant and antibacterial activity of leaves of Etlingera species (Zingiberaceae) in Peninsular Malaysia. Food Chemistry, 104(4), pp.1586-1593. doi: 10.1016/j.foodchem.2007.03.023.

Charon, M., 2006. Taxonomy and phylogeny of the genus curcuma L. (Zingiberaceae) with particular reference to its occurrence in Thailand. Prince of Songkla University.

Dermawaty, D.E., 2015. Potential Extract Curcuma (Curcuma xanthorrizal, Roxb) As Antibacterials. Medical Journal of Lampung University, 4(1), pp.5–11.

Devi, N. B., et al., 2014. Ethnomedicinal Utilization of Zingiberaceae in the Valley Districts of Manipur. IOSR Journal of Environmental Science, Toxicology And Food Technology (IOSR-JESTFT), 8(2), pp.21–23. doi: 10.9790/2402-08242123

Diastuti, H et al., 2019. Antifungal activity of Curcuma xanthorrhiza and Curcuma soloensis extracts and fractions. IOP Conference Series: Materials Science and Engineering, 509, pp. 1–5. doi: 10.1088/1757-899X/509/1/012047.

Hajiaghaalipour, F. et al., 2013.The Effect of Camellia sinensis on Wound Healing Potential in an Animal Model. Evidence-Based Complementary and Alternative Medicine : eCAM, 2013, 386734. doi: 10.1155/2013/386734

Hamdi, A.A.O., 2015. Chemical Constituents From The Rhizomes Of Curcuma zedoria And Curcuma purpurascens and Assessment of Their Biological Activities. University of Malaya.

Hong, L.-S. et al., 2014. Essential Oil Content of the Rhizome of Curcuma purpurascens Bl . (Temu Tis) and Its Antiproliferative Effect on Selected Human Carcinoma Cell Lines. The Scientific World Journal, 2014, 397430. doi: 10.1155/2014/397430.

Ibrahim, N.I. et al., 2018. Review Wound Healing Properties of Selected Natural Products. International Journal of Environmentsl Research snd Public Health, 15(2360). doi: 10.3390/ijerph15112360.

Jalip, I.S et al., 2013. Antioxidant Activity and Total Flavonoids Content of Curcuma Rhizome Extract. The 4th Green Technology Faculty of Science and Technology, Islamic of University State Maulana Malik Ibrahim Malang.

Jeon, W. et al., 2015. Curcuma aromatica Water Extract Attenuates Ethanol-Induced Gastritis via Enhancement of Antioxidant Status. Evidence-based complementary and alternative medicine : eCAM, 2015, 582496. doi: 10.1155/2015/582496.

Khan, R.A., 2012. Evaluation of flavonoids and diverse antioxidant activities of Sonchus arvensis. Chemistry Central Journal, 6(1), pp.1–7. doi: 10.1186/1752-153X-6-126.

Koller, E., 2009. Javanese medicinal plants used in rural communities. Universität Wien.

Lamore, S.D et al., 2010. The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells. Cell Stress and Chaperones, 15, pp.309–322. doi: 10.1007/s12192-009-0145-6.

Larsen, K. et al., 2000. Gingers of Peninsular Malaysia and Singapore, Natural History Publications (Borneo), p.135.

Larsen, K. & Larsen, S.S., 2006. Gingers of Thailand, Queen Sirikit Botanic Garden (QSBG).

Li, S., 2011. Chemical Composition and Product Quality Control of Turmeric (Curcuma longa L.). Pharmaceutical Crops, 5(1), pp.28–54. doi: 10.2174/2210290601102010028.

Longo, G.U. et al., 2011. Tissue engineered biological augmentation fortendon healing: a systematic review. British Medical Bulletin, 98, pp.31–59.

Mahalakshmi, S. et al., 2019. Isolation and Pharmacological Activities of Curcumin from Curcuma longa L. International Journal for Research in Applied Sciences and Biotechnology, 5(5), pp.7–17. doi: 10.31033/ijrasb.6.5.2

Mishra, R. et al., 2018. Genetic diversity, essential oil composition, and in vitro antioxidant and antimicrobial activity of Curcuma longa L. germplasm collections. Journal of Applied Research on Medicinal and Aromatic Plants, 10(June), pp.75–84. doi: 10.1016/j.jarmap.2018.06.003.

Moghadamtousi, S.Z. et al., 2014. A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin. BioMed Research International, 2014, 186864. doi: 10.1155/2014/186864

Nahak, G. & Sahu, R.K., 2011. Evaluation Of Antioxidant Activity In Ethanolic Extracts Of Five Curcuma Species. International Journal of Pharmacy, 2(12), pp. 243–248.

Padalia, R.C. et al., 2014. Volatile terpenoid compositions of leaf and rhizome of Curcuma amada Roxb. from Northern India. Journal of Essential Oil Research, 25(1), pp.17–22. doi: 10.1080/10412905.2012.747271.

Pal, J. et al., 2011. Hepatoprotective and antioxidant activity of Zingiber chrysanthum Rosec. rhizomes. Asian Journal of Traditional Medicines, 6(6), pp. 242–251.

Phuyal, N. et al., 2020. Total Phenolic, Flavonoid Contents, and Antioxidant Activities of Fruit, Seed, and Bark Extracts of Zanthoxylum armatum DC. Scientific World Journal, 2020, 8780704. doi: 10.1155/2020/8780704.

Policegoudra, R.S. et al., 2010. Antimicrobial, antioxidant, cytotoxicity and platelet aggregation inhibitory activity of a novel molecule isolated and characterized from mango ginger (Curcuma amada Roxb) rhizome. Journal of biosciences, 35(2), pp. 231–240. doi: 10.1007/s12038-010-0027-1.

Pramiastuti, O. et al., 2021. Aktivitas Antioksidan Ekstrak Etanol Temu Blenyeh. Prosiding Seminar Nasional Kesehatan 2021 Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Pekajangan, pp.29–37. doi: 10.48144/prosiding.v1i.618

Pramiastuti, O. & Murti, F.K., 2022. Fitokimia dan Aktivitas Antioksidan Ekstrak Temu Blenyeh (Curcuma purpurascens Blumae). Jurnal Ilmiah Kesehatan, 15(1), pp.12–22. doi: 10.48144/jiks.v15i1.627.

Prasad, S. & Aggarwal, B.B., 2011. Turmeric, the Golden Spice: From Traditional Medicine to Modern Medicine. In Herbal medicine: biomolecular and clinical aspects. 2nd edition. Boca Raton, FL: CRC Press/Taylor & Francis, Chapter 13. https://www.ncbi.nlm.nih.gov/books/NBK92752/.

Rajkumari, S. & Sanatombi, K., 2018. Nutritional value, phytochemical composition, and biological activities of edible Curcuma species: A review. International Journal of Food Properties, 20(3), pp.S2668–S2687. doi: 10.1080/10942912.2017.1387556.

Rana, M. et al., 2015. Turmerone enriched standardized Curcuma longa extract alleviates LPS induced inflammation and cytokine production by regulating TLR4-IRAK1-ROS-MAPK-NFκB axis. Journal of Functional Foods, 16, pp.152–163. doi: 10.1016/j.jff.2015.04.034.

Rosida, A., 2016. Pemeriksaan Laboratorium Penyakit Hati. Berkala Kedokteran, 12(1), p.123. doi: 10.20527/jbk.v12i1.364.

Rouhollahi, E. et al., 2014. Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats. BMC Complementary and Alternative Medicine, 14, 378, pp.1–10. doi: 10.1186/1472-6882-14-378

Rouhollahi, E. et al., 2015a. Curcuma purpurascens BI. rhizome accelerates rat excisional wound healing: Involvement of Hsp70/Bax proteins, antioxidant defense, and angiogenesis activity. Drug Design, Development and Therapy, 9, pp.5805–5813. doi: 10.2147/DDDT.S88196.

Rouhollahi, E. et al., 2015b. Inhibitory effect of Curcuma purpurascens BI. rhizome on HT-29 colon cancer cells through mitochondrial-dependent apoptosis pathway. BMC Complement Altern Med, 15, 15. doi: 10.1186/s12906-015-0534-6.

Rouhollahi, E. et al., 2015c. The chemopreventive potential of Curcuma purpurascens rhizome in reducing azoxymethane-induced aberrant crypt foci in rats. European Journal of Cancer, 51, e8. doi: 10.1016/j.ejca.2015.06.028.

Rouhollahi, E. et al., 2015d. The chemopreventive potential of Curcuma purpurascens rhizome in reducing azoxymethane-induced aberrant crypt foci in rats. Drug Design, Development and Therapy, 9, pp.3911–3922. doi: 10.2147/DDDT.S84560.

Rouhollahi, E. et al., 2015e. Dichloromethane Curcuma purpurascens BI Rhizome Extract Prevents Thioacetamide-Induced Liver Cirrhosis in Rats. in Conference: 2015 Golden Helix Symposium - Next Generation Pharmacogenomics At: Kuala Lumpur, Malaysia. Public Health Genomics 18.

Rouhollahi, E., 2016. Biological Activities Of Curcuma purpurascens Bl Rhizome Extract Using In Vitro and In Vivo Models. University Of Malaya Kuala Lumpur.

Saensouk, P. et al., 2015. Pollen morphology of the genus Curcuma (Zingiberaceae) in Northeastern Thailand. Science Asia, 41(2), pp.87–92. doi: 10.2306/scienceasia1513-1874.2015.41.087.

Saikia, B. & Borthakur, S.K., 2010. Use of medicinal plants in animal healthcare- A case study from Gohpur, Assam. Indian Journal of Traditional Knowledge, 9(1), pp.49–51. http://nopr.niscpr.res.in/handle/123456789/7153

Sasikumar, B., 2005. Genetic resources of Curcuma : diversity, characterization and utilization. Plant Genetic Resources, 3(2), pp. 230–251. doi: 10.1079/pgr200574.

Setyawan, A.D., 2003. Diversity of essential oils constituent of Curcuma. Biofarmasi Journal of Natural Product Biochemistry, 1(2), pp.44–49. doi: 10.13057/biofar/f010202.

Sihanat, A., Theanphong, O. & Rungsihirunrat, K., 2020. Assessment of phylogenetic relationship among twenty Curcuma species in Thailand using amplified fragment length polymorphism marker. Journal of Advanced Pharmaceutical Technology and Research, 11(3), pp.134–141. doi: 10.4103/japtr.JAPTR_24_20.

Sinaga, E., Suprihatin & Rastuti, M.R., 2018. Kadar Flavonoid Total, Daya Antioksidan dan Daya Hepatoprotektif Ekstrak Etanol Rimpang Temu Tis (Curcuma purpurascens). Konggres XX dan Pertemuan Ilmiah Tahunan Ikatan Apoteker Indonesia 2018, p.13.

Skornickova, J.L. et al., 2007. Chromosome numbers and genome size variation in Indian species of Curcuma (Zingiberaceae). Annals of Botany, 100(3), pp.505–526. doi: 10.1093/aob/mcm144.

Srivastava, S. et al., 2006. Pharmacognostic Evaluation of Curcuma aeurigenosa Roxb. Natural Product Sciences, 12(3), pp.162–165.

Suprihatin, Tambunan, C. & Sinaga, E., 2020. Acute and Subchronic Toxicity Of Temu Tis (Curcuma Purpurascens Bl.) Rhizome in Mouse (Rattus Norvegicus). Journal of Tropical Biodiversity, 1(1), pp.47–62.

Vibrianti, Y., 2005. Isolasi dan Identifikasi Fraksi Aktif Antijamur dalam Rimpang Temu Tis (Curcuma purpurascens Bl.). Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Sebelas Maret.

Widyastuti, I. et al., 2020. Antioxidant Activity of Temulawak (Curcuma xanthorrhiza Roxb.) and its Classification with Chemometrics. Indonesian Journal of Chemometrics and Pharmaceutical Analysis, 1(1), p.29. doi: 10.22146/ijcpa.507.

Xiang, Z. et al., 2011. Metabolomics study on quality control and discrimination of three curcuma species based on gas chromatograph-mass spectrometry. Phytochemical Analysis, 22(5), pp.411–418. doi: 10.1002/pca.1296.



DOI: https://doi.org/10.22146/jtbb.75891

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