Efektivitas Infusa Daun Talok (Muntingia calabura) dalam Menghambat Pertumbuhan Bakteri Klebsiella pneumoniae

https://doi.org/10.22146/jntt.44933

Fitri Nadifah(1*), Desto Arisandi(2), Siti Fatimah(3), Dani Setiawan(4)

(1) Program Studi D3 Analis Kesehatan STIKES Guna Bangsa Yogyakarta, Indonesia
(2) Program Studi D3 Analis Kesehatan STIKES Guna Bangsa Yogyakarta, Indonesia
(3) Program Studi D3 Analis Kesehatan STIKES Guna Bangsa Yogyakarta, Indonesia
(4) Program Studi D3 Analis Kesehatan STIKES Guna Bangsa Yogyakarta, Indonesia
(*) Corresponding Author

Abstract


Klebsiella pneumoniae is one of the most bacteria found in urine of Urinary Tract Infection (UTI) Patients. Study in many countries has found that this species become resistant to more than one antibiotics. This research goal is to know the effectiveness of talok (Muntingia calabura) infused water inhibiting the growth of K. pneumoniae. This was an experimental study using K. pneumoniae bacteria isolated from urine samples using diffuse agar method. The concentration of talok infused water was varied from 25-100% and the antibiotics used was cefotaxime, meropenem and chloramphenicol. The inhibition activity was measured by the diameter of inhibition zone. The results show that K. pneumoniae is still give sensitive response to antibiotic treatments. While the inhibition zone from talok infused water treatments can be categorized in middle and strong activity. From this study we can conclude that talok infused water potential in inhibiting the growth of K. pneumoniae. Future study still needed to develop this potential, especially for the bacteria that has been resistant to some antibiotics.

Keywords


infused water; talok; K. pneumoniae; UTI

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References

Adisasmito, A. W., & Tumbelaka, A. R. (2006). Penggunaan antibiotik khusunya pada infeksi bakteri gram negatif di ICU anak RSAB Harapan Kita. Sari Pediatri, 8(6), 127–134.

 

Dasgupta, A. (2012). Advances in Clinical Chemistry. (G. S. Makowski, Ed.). Cambridge: Elsevier Inc.

 

Davis, W. W., & Stout, T. R. (1971). Disc plate method of microbiological antibiotic assay. I. Factors influencing variability and error. Applied Microbiology, 22(4), 659–65. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=376382&tool=pmcentrez&rendertype=abstract

 

Kalbemedical. (2017). Meropenem-Extended-Infusion Memberikan-Efek-Lebih-Baik. Retrieved from www.kalbemed.com/News/tabid/229/id/1686/

 

Kumala, S., Raisa, N., Rahayu, L., & Kiranasari, A. (2009). Uji Kepekaan Bakteri yang Diisolasi Dari Urin Penderita Infeksi Saluran Kemih (ISK) Terhadap Beberapa Antibiotika. Majalah Ilmu Kefarmasian, VI(2), 45–55. https://doi.org/1693-9883

 

Kurniawan, I., Sarwiyono, & Surjowardojo, P. (2010). Pengaruh teat dipping menggunakan dekok daun kersen (Muntingia calabura L.) terhadap tingkat kejadian mastitis. Jurnal-Jurnal Ilmu Peternakan, 23(3), 27–31.

 

LeFrock, J. L., Prince, R. A., & Leff, R. D. (1982). Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy, 2(4), 174–84.

 

Prawira, M. Y., Sarwiyono, & Surjawordojo, P. (2013). Daya Hambat Dekok Daun Kersen (Muntingia calabura L.) terhadap Pertumbuhan Bakteri Staphylococcus aureus Penyebab Penyakit Mastitis pada Sapi Perah. Jurnal Wahana, 1(2).

 

Sanchez, G. V, Master, R. N., Clark, R. B., Fyyaz, M., Duvvuri, P., Ekta, G., & Bordon, J. (2013). Klebsiella pneumoniae antimicrobial drug resistance, United States, 1998–2010. Emerg Infect Dis, 19(1), 133–136.

 

Seidel, V. (2012). Chapter 2. Methods Mol Biol., 864, 27–41. https://doi.org/10.1007/978-1-61779-624-1

 

Sharma, N., Gupta, A., Walia, G., & Bakhshi, R. (2016). Pattern of Antimicrobial Resistance of Escherichia coli Isolates from Urinary Tract Infection Patients: A Three Year Retrospective Study. Journal of Applied Pharmaceutical Science, 6(01), 62–65. https://doi.org/10.7324/JAPS.2016.600110

 

Sondakh, F. A., Fatimawati, & Wewengkang, D. S. (2016). Uji Kepekaan Bakteri yang Diisolasi dan Diidentifikasi dari Urin Penderita Infeksi Saluran Kemih di RSUP Prof. Dr. R. D. Kandou Manado terhadap Antibiotik Amoksisilin, Gentamisin dan Seftriakson. PHARMACON, 5(4), 123–129.

 

Zhanel, G. G., Simor, A. E., Vercaigne, L., & Mandell, L. (1998). Imipenem and meropenem: Comparison of in vitro activity, pharmacokinetics, clinical trials and adverse effects. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses, 9(4), 215–28. Retrieved from http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3250889&tool=pmcentrez&rendertype=abstract



DOI: https://doi.org/10.22146/jntt.44933

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