Asupan zat gizi mikro dengan fungsi kognitif pada lanjut usia

https://doi.org/10.22146/ijcn.18218

Ade Rahmawati(1*), I Dewa Putu Pramantara(2), Martalena Purba(3)

(1) Fakultas Kesehatan Masyarakat, Univesitas Wiralodra Indramayu
(2) Bagian Penyakit Dalam Rumah Sakit Umum Pusat Dr. Sardjito, Yogyakarta
(3) Instalasi Gizi Rumah Sakit Umum Pusat Dr. Sardjito, Yogyakarta
(*) Corresponding Author

Abstract


Background: The elderly population in Indonesia increased signifi cantly in the last two decades as the life expectancy increase from 66.7 years to 70.5 years with impact to the emergence of diseases in the elderly. One of them is degradation of cognitive function that may disrupt productivity, daily activities, and quality of life of the elderly. Adequate micronutrients intake may help in maintaining cognitive function.

Objectives: To identify association between intake of micronutrients (vitamin B6, folate, vitamin C, and vitamin E) and cognitive function of the elderly at Among Yuswa Club of Banteng Baru, District of Sleman.

Methods: This was an observational study with cross sectional design. Subjects were elderly people at Among Yuswa Club of Banteng Baru, District of Sleman. Data on cognitive function was obtained using the Mini Mental State Examination (MMSE) and intake of micronutrients were collected using Semi Qualitative Food Frequency Questionnaire (SQFFQ). The data was analysed by chi square and logistic regression tests.

Results: The result showed statistically signifi cant association between cognitive function and intake of vitamin B6 (p=0.010; RP=2.514; 95%CI=1.133-5.575), vitamin C intake (p=0.011; RP=3.039; 95%CI=1.454-6.353) and vitamin E intake (p=0.021; RP=1.266; 95%CI=1.057-1.516); meanwhile folate intake has no signifi cant association with cognitive function (p>0.05).

Conclusion: There were signifi cant associations between intake of vitamin B6, vitamin C and vitamin E with cognitive function. There was no signifi cant association found between intake of folate and cognitive function in the elderly.


Keywords


micronutrients; cognitive function; elderly

Full Text:

PDF


References

Departemen Kesehatan RI. Pedoman penanggulangan masalah kesehatan intelegensia akibat gangguan degeneratif. Jakarta: Direktorat Bina Gizi Masyarakat DitjenBinkesmas Depkes RI; 2010.

Turana YM. Pemeriksaan status mini mental pada usia lanjut di Jakarta. Medika 2004;30(9):563-8.

Requejo AM, Ortega RM, Robles F, Navia B, Aparicio A. Influence of nutrition on cognitive function in a group of elderly, independently living people. Eur J Clin Nutr 2003;57(1):S54-7.

Ramos MI, Allen LH, Mungas DM, Jagust WJ, Haan MN, Green R, Miller JW. Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino study on aging 1-3. Am J Clin Nutr 2005;82(6):1346-52.

Logroscino G, Kang JH, Grodstein F. Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. BMJ 2004;328:548.

Madiyono B, Moeslichan S, Sastroasmoro S, Budiman I, Purwanto SH. Dalam: Sastroasmoro S, Ismael S. Dasar- dasar metodologi penelitian klinis. Jakarta: Sagung Seto; 2008.

Lumbantobing SM. Kecerdasan pada usia lanjut dan demensia. Jakarta: Balai Penerbit FKUI; 2001.

Almatsier S. Prinsip dasar ilmu gizi. Jakarta: Gramedia Pustaka Utama; 2009.

Rabe B, Thamrin MH, Gross R, Solomons NW, Schultink W. Body mass index of the elderly derived from height and from armspan. Asia Pac J Clin Nutr 1996;5(2):79-83.

Aswin S. Perubahan struktural dan fungsional otak menua strategi optimalisasi otak menua menuju hidup sehat. Kongres Nasional III dan Temu Ilmiah Nasional II, Medika. Yogyakarta: Fakultas Kedokteran UGM; 2004.

Lee S, Kawachi I, Berkman LF, Grodstein F. Education, other socioeconomic indicators, and cognitive function. Am J Epidemiol 2003;157(8):712-20.

Farmer ME, Kittner SJ, Rae DS, Bartko JJ, Regier DA. Education and change in cognitive function. Ann Epidemiol 1995;5(1):1-7.

Swanwick GR, Coen RF, Maguire CP, Kirby M, Walsh JB, O’neill D, Coakly D, Lawlor BA. The association between demographic factors, disease severity and the duration of symptoms at clinical presentation in elderly people with dementia. Age Ageing 1999;28(3):295-9.

Freidl W, Schmidt R, Stronegger WJ, Irmler A, Reinhart B, Koch M. Mini mental state examination: influence of sociodemographic, environmental and behavioral factors, and vascular risk factors. J Clin Epidemiol 1996;49(1):73-8.

Paul C, Ribeiro O, Santos P. Cognitive impairment in old people living in the community. Arch Gerontol Geriatr 2010;51(2):121-4.

Czlonkowska A, Ciesielska A, Joniec I. Influence of estrogen on neurodegenerative processes. Med Sci Monit 2003;9(10):247-56.

Irving GF, Olsson BA, Cederholm T. Nutritional and cognitive status in elderly subjects living in service flats, and the effect of nutrition education on personal. Gerontology 1999;45:187-94.

Grodstein F, Chen J, Willett WC. High-dose antioxidant supplements and cognitive function in community- dwelling elderly women. Am J Clin Nutr 2003;77(4):975-84.

Riggs KM, Spiro A, Tucker K, Rush D. Relations of vitamin B-12, vitamin B-6, folate and homocysteine to cognitive performance in the normative aging study. Am J Clin Nutr 1996;63(3):306-14.

Smith AD, Smith SM, Jager CA, Whitbread P, Johnston C, Agacinski G, Oulhaj A, Bradley KM, Jacoby R, Refsum H. Homocysteine-lowering by b vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. PLoS One2010;5(9):1-10.

De Lau LML, Refsum H, Smith AD, Johnston C, Breteler MMB. Plasma folat concentration and cognitive performance: Rotterdam scan study. Am J Clin Nutr 2007;86(3):728-34.

Paleologos M, Cumming RG, Lazarus R. Cohort study of vitamin C intake and cognitive impairment. Am J Epidemiol 1998;148(1):45-50.

Young LS, Woodside JV. Antioxidant in health and disease. J Clin Pathol 2001;54:176-86.

Winarsi H. Antioksidan alami & radikal bebas. Yogyakarta: Kanisius; 2007.

Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA. Relation of the tocopherol forms to incident alzheimer disease and to cognitive change. Am J Clin Nutr 2005;81(2):508-14.

Aparicio A, Bermejo LM, Rodriguez ER, Andres P, Ortega RM, Sobaler AML. Influenced of vitamin E status on cognitive function in elderly people. Elderly Nutrition 2006;19(6):30-2.



DOI: https://doi.org/10.22146/ijcn.18218

Article Metrics

Abstract views : 1684 | views : 2773

Refbacks

  • There are currently no refbacks.




Copyright (c) 2017 Jurnal Gizi Klinik Indonesia (The Indonesian Journal of Clinical Nutrition)

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Jurnal Gizi Klinik Indonesia (JGKI) Indexed by:
 
 Crossref   Google Scholar Indonesian Scientific Journal Database (ISJD) Indonesia OneSearch (IOS)  CORE   

  Creative Commons License

JGKI is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

free
web stats View My Stats