Editorial Board Member: Prof. Dietmar Haltrich

Curriculum Vitae



Personal details

Acad. Degree:       Univ. Prof. Dr.
Current position:    Professor (Head of Department)




Academic Credentials

2001                               Habilitation in Biotechnology & Microbial Physiology, BOKU – University of Natural Resources and Life Sciences
Thesis Title: “Production of Carbohydrate-Based Food Ingredients and Modification of Carbohydrate-Containing Foods by Enzyme Technology”
1993 Dr. techn., University of Technology Graz, Institute of Biotechnology
Thesis Title: “Studies on the Formation of β-(1,3)-D-Glucans and Hemi-cellulolytic Enzymes by Sclerotium rolfsii and Schizophyllum commune”
1988 Dipl. Ing. (equivalent to Master), University of Technology Graz, Institute of Biotechnology
   

Previous and Current Position
 
1991-1992 Teaching Assistant at the Institute of Biotechnology, University of Technology Graz
1993-2001 Teaching Assistant at the Institute of Biotechnology, University of Technology Graz
1993-2001  Assistant Professor at the Inst. of Food Technology, BOKU
2001-2004  Associate Professor at the Department of Food Science and Technology, BOKU
since 2004 Professor at the Department of Food Science and Technology, BOKU
since 2007 Head of the Food Biotechnology Laboratory within the Department of Food Sciences and Technology, BOKU
since 2010 Deputy Speaker of the International PhD Programme Biomolecular Technology of Proteins – BioToP
since 2012 Adjunct Professor, Genetic Engineering Program of the Graduate School, Kasetsart University, Bangkok, Thailand
since 2016 Adjunct Professor, University of the Philippines Los Baños, Philippines
since 2019 Head of the Departement of Food Science and Technology, BOKU
   

Visiting Fellowships and Awards
 
1999  Prof. Anton Kurir Award
2000 Agrana Forschungspreis
2002 Fischer Innovationspreis
2004 Visiting Professor at Hanoi University of Science and Technology, Hanoi, Vietnam
2005  Visiting Professor at the National University of Singapore
2006 Visiting Professor at Kasetsart University, Bangkok, Thailand
2007 Visiting Professor at Silpakorn University, Nakhon Pathom, Thailand
2008 Visiting Professor at Hanoi University of Science and Technology, Hanoi, Vietnam
2009  Visiting Professor at Silpakorn University, Nakhon Pathom
2011 Visiting Professor at Suranaree University of Technology, Nakhon Ratchasima, Thailand
2013/14 Visiting Professor at Suranaree University of Technology, Thailand
2015 Visiting Professor at Florida A&M University, Tallahassee, USA
2018 Visiting Professor at Brawijaya University, Malang, Indonesia

 

Memberships in Academic Societies and Editorships

Biocatalysis Division of the European Federation of Biotechnology, Board MemberJournal of Biotechnology, Member of the Editorial Board Indonesian Journal of Biotechnology, Member of the Editorial BoardSuranaree Journal of Science and Technology, Member of the Editorial Board Microorganisms, Member of the Editorial Board


Research Interest

Structure and function of flavin-containing oxidoreductases with focus on carbohydrate oxidases and dehydrogenases; b-galactosidases from lactobacilli; enzyme engineering; application of enzymes for biocatalysis and biosensors; gene expression in lactobacilli

 

Fields of Expertise

Enzymes and technological application of enzymes; food biotechnology; enzyme characterisation; enzyme kinetics; enzyme engineering and improvement using different approaches; protein expression systems, especially food-grade systems.

Specific expertise with the following groups of enzymes: hydrolases (b-galactosidases and related enzymes) as well as oxidoreductases (FAD-dependent enzymes, copper-containing enzymes)

 

Selected Research Projects Funded in the Past

1. ‘Ancestral sequence reconstruction: understanding shifts in substrate specificity of GMC oxidoreductases’, Austrian Science Funds, 2020-2023
2. ‘Reconstruction of ancestral oxidases and directed enzyme evolution towards stable lactate biosensors’, Austrian Research Promotion Agency FFG, 2020-2022
3. ‘Stabilisation of redox enzymes for long-term implantable biosensors’, Austrian Research Promotion Agency FFG, 2018-2021
4. ‘Recreation of ancestral members of the GMC family of FAD-dependent oxidoreductases’, project within the Doctoral Programme – plus Biomolecular Technology of Proteins (BioToP, http://biotop.boku.ac.at/) funded by the Austrian Science Fund FWF, 2014-2018
5. ‘Three-Dimensional Nanobio-Structure Based Self-contained Devices for Biomedical Applications’, European Commission, FP7-NMP-2008-SMALL-2, 2009-2012

 

List of Publications (Last 3 years)

1. Geiss, A.F.; Reichhart, T.M.B.; Pejker, B.; Plattner, E.; Herzog, P.L.; Schulz, C.; Ludwig, R.; Felice, A.K.G.; Haltrich, D. (2021) Engineering the turnover stability of cellobiose dehydrogenase toward long-term bioelectronic applications. ACS Sustain. Chem. Eng. 9, 7086-7100; doi: 10.1021/acssuschemeng.1c01165

2. Pongsapipatana, N.; Charoenwattanasatien, R.; Pramanpol, N.; Nguyen, T.H.; Haltrich, D.; Nitisinprasert, S.; Keawsompong, S. (2021) Crystallization, structural characterization and kinetic analysis of a GH26 β-mannanase from Klebsiella oxytoca KUB-CW2-3. Acta Crystallogr. D Struct. Biol. 77:1425-1436. doi: 10.1107/S2059798321009992

3. Tran, A.M.; Unban, K.; Kanpiengjai, A.; Khanongnuch, C.; Mathiesen, G.; Haltrich, D.; Nguyen, T.H. (2021) Efficient secretion and recombinant production of a lactobacillal α-amylase in Lactiplantibacillus plantarum WCFS1: Analysis and comparison of the secretion using different signal peptides. Front Microbiol. 12: 689413; doi: 10.3389/fmicb.2021.689413

4. Watthanasakphuban, N.; Virginia, L.J.; Haltrich, D.; Peterbauer, C. (2021) Analysis and reconstitution of the menaquinone biosynthesis pathway in Lactiplantibacillus plantarum and Lentilactibacillus buchneri. Microorganisms 9:1476; doi: 10.3390/microorganisms9071476

5. Widodo, W.; Ariani, A.L.; Widianto, D.; Haltrich, D. (2021) Genomic Comparison of Lactobacillus casei AP and Lactobacillus plantarum DR131 with Emphasis on the Butyric Acid Biosynthetic Pathways. Microorganisms, 9:425; doi: 10.3390/microorganisms9020425

6. Wijayanti, S.D.; Sützl, L.; Duval, A.; Haltrich, D. (2021) Characterization of fungal FAD-dependent AA3_2 glucose oxidoreductases from hitherto unexplored phylogenetic clades. J. Fungi 7, 873; doi: 10.3390/jof7100873

7. Yogeswara, I.B.A.; Kittibunchakul, S.; Rahayu, E.S.; Domig, K.J.; Haltrich, D.; Nguyen, T.H. (2021) Microbial production and enzymatic biosynthesis of gamma-aminobutyric acid (GABA) using Lactobacillus plantarum FNCC 260 isolated from Indonesian fermented foods. Processes, 9:22, doi: 10.3390/pr9010022

8. Abrera, A.; Chang, H; Kracher, D.; Ludwig, R.; Haltrich, D. (2020) Characterization of pyranose oxidase variants for bioelectrocatalytic applications, Biochim. Biophys. Acta, 1868: 140335; doi: 10.1016/j.bbapap.2019.140335

9. Abrera, A.; Sützl, L.; Haltrich, D. (2020) Pyranose oxidase: a versatile sugar oxidoreductase for bioelectrochemical applications. Bioelectrochemistry, 132: 107409; 10.1016/j.bioelechem.2019.107409

10. Kanpiengjai, A.; Khanongnuch, C.; Lumyong, S.; Haltrich, D.; Nguyen, T.H.; Kittibunchakul, S. (2020) Co-production of gallic acid and a novel cell-associated tannase by a pigment-producing yeast, Sporidiobolus ruineniae A45.2. Microb. Cell Fact. 19:95; doi: 10.1186/s12934-020-01353-w

11. Kittibunchakul, S.; van Leeuwen, S.S.; Dijkhuizen, L.; Haltrich, D.; Nguyen, T.H. (2020) Structural comparison of different galacto-oligosaccharide mixtures formed by beta-galactosidases from lactic acid bacteria and bifidobacteria. J. Agr. Food Chem. 68, 4437-4446; doi: 10.1021/acs.jafc.9b08156

12. Schütz, G.; Haltrich, D.; Atanasova, L. (2020) Influence of spore morphology on spectrophotometric quantification of Trichoderma inocula. Biotechniques 68, 279-282; doi: 10.2144/btn-2019-0152

13. Yogeswara, I.B.A.; Maneerat, S.; Haltrich, D. (2020) Glutamate decarboxylase from lactic acid bacteria - A key enzyme in GABA synthesis. Microorganisms. 8: 1923; doi: 10.3390/microorganisms8121923

14. Herzog, P.L.; Sützl, L.; Eisenhut, B.; Maresch, D.; Haltrich, D.; Obinger, C.; Peterbauer, CK (2019) Versatile oxidase and dehydrogenase activities of bacterial pyranose 2-oxidase facilitate redox cycling with manganese peroxidase in vitro. Appl. Environ. Microbiol. 85: e00390-19; doi: 10.1128/AEM.00390-19

15. Kanpiengjai, A.; Unban, K.; Nguyen, T.H.; Haltrich, D.; Khanongnuch, C (2019) Expression and biochemical characterization of a new alkaline tannase from Lactobacillus pentosus. Protein Expr. Purif.  157, 36-41; doi: 10.1016/j.pep.2019.01.005

16. Nguyen, H.M.; Pham, M.L.; Stelzer, E.M.; Plattner, E.; Grabherr, R.; Mathiesen, G.; Peterbauer, C.K.; Haltrich, D.; Nguyen, T.H. (2019) Constitutive expression and cell-surface display of a bacterial β-mannanase in Lactobacillus plantarum. Microb. Cell Fact.18:76; doi:10.1186/s12934-019-1124-y

17. Novak, B.; Rainer, V.; Sulyok, M.; Haltrich, D.; Schatzmayr, G.; Mayer, E. (2019) Twenty-eight fungal secondary metabolites detected in pig feed samples: their occurrence, relevance and cytotoxic effects in vitro. Toxins 11:537; doi: 10.3390/toxins11090537

18. Suphatpahirapol, C.; Nguyen, T.H.; Tansiri, Y.; Yingchutrakul, Y.; Roytrakul, S.; Nitipan, S.; Wajjwalku, W.; Haltrich, D.; Prapong, S.; Keawsompong, S. (2019) Expression of a leptospiral leucine-rich repeat protein using a food-grade vector in Lactobacillus plantarum, as a strategy for vaccine delivery. 3 BIOTECH 9:324; doi: 10.1007/s13205-019-1856-8

19. Sützl, L.; Foley, G.; Gillam, E.M.J.; Bodén, M.; Haltrich, D. (2019) The GMC superfamily of oxidoreductases revisited: analysis and evolution of fungal GMC oxidoreductases Biotechnol. Biofuels 12:118, doi:10.1186/s13068-019-1457-0