The role of family caregivers in medication adherence of elderly in Asian setting: a scoping review
Abstract
Family caregivers for elderly play a very important role in implementing drug adherence, especially in Asian countries. Various determinants of medication adherence included caregivers as family support. Although the relationship between family support is not always significant, understanding the factors of family caregivers on medication adherence is important, especially when improving adherence in Asian countries.
The following scoping review was conducted to provide an overview of caregivers, and its relationship to medication adherence in Asian settings. PRISMA-ScR guideline and checklist was used for the search process and to guide reporting. Review selection and characterization were performed by reviewers independently. In total, 22 papers were included in the review, published from 2011 to 2021. The studies varied in terms of purpose, methodology, and detail of reporting.
Family caregiver is an important determinant of medication adherence, especially for areas where extended family culture is still strong, such as in Asia. Understanding the local culture, aspects of family burden and economic, as well as the role of the health profession, especially pharmacists in health services are needed to improve adherence. Therefore, further research with quality methods is needed.
References
Willis E, Price K, Bonner R, Henderson J, Gibson T, Hurley J, et al. Meeting residents ' care needs: A study of the requirement for nursing and personal care staff. Australian Nursing and Midwifery Federation. 2016. Available from: https://agedcare.royalcommission.gov.au/system/files/2020-08/ANM.0001.0001.3151.pdf
Chen EYH, Simon Bell J, Ilomaki J, Keen C, Corlis M, Hogan M, et al. Medication regimen complexity in 8 Australian residential aged care facilities: Impact of age, length of stay, comorbidity, frailty, and dependence in activities of daily living. Clin Interv Aging 2019;14:1783-95. https://doi.org/10.2147/CIA.S216705
Advinha AM, De Oliveira-Martins S, Mateus V, Pajote SG, Lopes MJ. Medication regimen complexity in institutionalized elderly people in an aging society. Int J Clin Pharm 2014;36(4):750-6. https://doi.org/10.1007/s11096-014-9963-4
Herson M, Bell JS, Tan ECK, Emery T, Robson L, Wimmer BC. Factors associated with medication regimen complexity in residents of long-term care facilities. Eur Geriatr Med 2015;6(6):561-4. http://doi.org/10.1016/j.eurger.2015.10.003
Awad A, Alhadab A, Albassam A. Medication-related burden and medication adherence among geriatric patients in Kuwait: A cross-sectional study. Front Pharmacol. 2020;11(August):1-13. https://doi.org/10.3389/fphar.2020.01296
Chisholm-Burns MA, Spivey CA. The cost of medication nonadherence: consequences we cannot afford to accept. J Am Pharm Assoc 2012;52(6):823-6. https://doi.org/10.1331/JAPhA.2012.11088
Al-Noumani H, Alharrasi M, Lazarus ER, Panchatcharam SM. Factors predicting medication adherence among Omani patients with chronic diseases through a multicenter cross-sectional study. Sci Rep 2023;13(1):7067. https://doi.org/10.1038/s41598-023-34393-4
Griva K, Ng HJ, Loei J, Mooppil N, McBain HNS. Managing treatment for end-stage renal disease--a qualitative study exploring cultural perspectives on facilitators and barriers to treatment adherence. Psychol Health 2013;28(1):13-29. https://doi.org/10.1080/08870446.2012.703670
Kugler C, Maeding I RC. Non-adherence in patients on chronic hemodialysis: an international comparison study. J Nephrol. 2011;24(3):366-75. https://doi.org/10.5301/JN.2010.5823
Yoon S, Kwan YH, Yap WL, Lim ZY, Phang JK, Loo YX, et al. Factors influencing medication adherence in multi-ethnic Asian patients with chronic diseases in Singapore: A qualitative study. Front Pharmacol 2023; 14(March):1-11. https://doi.org/10.3389/fphar.2023.1124297
Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Ann Intern Med 2018;169(7):467-73. https://doi.org/10.7326/M18-0850
Withidpanyawong U, Lerkiatbundit S, Saengcharoen W. Patient education and counseling family-based intervention by pharmacists for type 2 diabetes : a randomised controlled trial. Patient Educ Couns 2019;102(1):85-92. https://doi.org/10.1016/j.pec.2018.08.015
Aloudah NM, Scott NW, Aljadhey HS, Araujo-Soares V, Alrubeaan KA, Watson MC. Medication adherence among patients with Type 2 diabetes: A mixed methods study. PLoS One 2018; 13(12):e0207583. https;//doi.org/10.1371/journal.pone.0207583.
Bastani P, Bikineh P, Mehralian G, Sadeghkhani O, Rezaee R. Medication adherence among the elderly : applying grounded theory approach in a developing country. J Pharm Policy Pract 2021;1-8. https://doi.org/10.1186/s40545-021-00340-9
Ben-Natan M NI. Factors affecting older persons' adherence to prescription drugs in Israel. Nurs Heal Sci 2011;13(2):164-9. https://doi.org/10.1111/j.1442-2018.2011.00594.x
Hussain S, Jamal SZ, Qadir F. Medication adherence in post myocardial infarction patients. J Ayub Med Coll Abbottabad 2018; 30(4):552-7. PMID: 30632336.
Johnson J, Vijayakumar K, Nujum ZT, Madhavanpillai P. Compliance and its determinants to pharmacologic management of hypertension. IJCH. 2019;31(01). https://doi.org/10.47203/IJCH.2019.v31i01.011
Jun J, Koh K, Legido-quigley H. Access and adherence to medications for the primary and secondary prevention of atherosclerotic cardiovascular disease in Singapore : a qualitative study. Patient Prefer Adherence 2018; 12:2481-98. https://doi.org/10.2147/PPA.S176256
Leung DY, Bai X, Leung AY, Liu BC CI. Prevalence of medication adherence and its associated factors among community-dwelling Chinese older adults in Hong Kong: Medication adherence in Chinese elderly. Geriatr Gerontol Int 2015; 15(6):789-96. https://doi.org/10.1111/ggi.12342
Woodham N, Taneepanichskul S, Somrongthong R, Auamkul N. Medication adherence and associated factors among elderly hypertension patients with uncontrolled blood pressure in rural area, Northeast Thailand. JHR 2018; 32(6):449-58. https://doi.org/10.1108/JHR-11-2018-085
Anggriani, Rahmawati F, Wahab IA. Aspek beban pengasuh pasien geriatri dan hubungannya terhadap kepatuhan pengobatan pada etnis Bugis di Kecamatan Wajo Sulawesi Selatan. Maj Farm 2021;17(2):175-81.
Alam RI, Jama F. Analisis faktor yang mempengaruhi ketidakpatuhan berobat lansia penderita hipertensi di wilayah kerja Puskesmas Pampang. JIKP. 2015;09(2):115-25.
Apsari DP, Putra IGNMSW, Maharjana IBN. Hubungan dukungan keluarga dan peran tenaga kefarmasian terhadap kepatuhan minum obat antihipertensi. J Ilm Medicam. 2021; 7(1):19-26. https://doi.org/10.36733/medicamento.v7i1.1499
Dolo LS, Yusuf A, Azis R. Analisis faktor memengaruhi kepatuhan berobat lansia penderita hipertensi pada masa pandemi COVID-19 di Puskesmas Bulili Kota Palu. Prepotif: J Kesehat Masy 2021;5(2):828-42. https://doi.org/10.31004/prepotif.v5i2.1890
Firdausi AZ, Sriyono S, Asmoro CP. Hubungan dukungan keluarga dengan kepatuhan melakukan latihan fisik dan terapi insulin pada pasien diabetes melitus tipe 1 di Poliklinik Penyakit Dalam RSUD dr. Abdoer Rahem Situbondo. CMSNJ 2019; 4(2): 1-8.
Ifrohatis S, Juanita, Nurhasannah. Dukungan sosial keluarga dan kepatuhan minum obat pada lansia hipertensi. Idea Nurs J 2019; 10(2):9-14. https://doi.org/10.32584/jikk.v2i2.411
Makkulawu A, Setiadi AP, Rahardjo TBW, Setiawan E. Analisis profil dan faktor-faktor yang memengaruhi perilaku kepatuhan pengobatan untuk pasien diabetes mellitus lanjut usia. J Kefarmasian Indones 2019;114-25. https://doi.org/10.22435/jki.v9i2.405
Nade MS, Rantung J. Dukungan keluarga dengan kepatuhan minum obat tuberulosis paru di wilayah kerja Puskesmas Gading Rejo. CHMK Nurs Sci J 2020; 4(1):1-7. https://doi.org/10.51997/jk.v7i1.57
Oktaviani NPW, Nopindrawati NPN, Trisnadewi NW, Adiputra IMS. Dukungan keluarga mengontrol kepatuhan minum obat anti hipertensi pada lansia selama pandemi COVID-19. J Keperawatan 2021; 13:69-77.
Prabasari NA. Self efficacy, self care management, dan kepatuhan pada lansia hipertensi (studi fenomenologi). J Keperawatan Malang 2021; 6(1):1-10. https://doi.org/10.36916/jkm.v6i1.115
Sulistyana CS. Hubungan dukungan keluarga dengan kepatuhan minum obat dan kontrol diit penderita hipertensi. J Kesehat Holist 2019; 3(2):28-36. https://doi.org/10.33377/jkh.v3i2.51
Sumantra IG, Kumaat LT, Bawotong J. Hubungan dukungan informatif dam emosional keluarga dengan kepatuhan minum obat pada lansia hipertensi di Puskesmas Ranomuut Kota Manado. J Keperawatan Unsrat 2017;5(1):113151.
Widyaningrum D, Retnaningsih D, Tamrin. Hubungan dukungan keluarga dengan kepatuhan minum obat pada lansia penderita hipertensi. J Ilmu Keperawatan Komunitas 2019;2(2):21-6. https://doi.org/10.32584/jikk.v2i2.411
Dewi DM. The representation of patriarchy in indonesian children folk tales from Sumatra Island. Ling Cult. 2019;13(3):167. https://doi.org/10.21512/lc.v13i3.5646
Kvarnström K, Westerholm A, Airaksinen M, Liira H. Factors contributing to medication adherence in patients with a chronic condition: A scoping review of qualitative research. Pharmaceutics. 2021;13(7):1-41. https://doi.org/10.3390/pharmaceutics13071100
Yuniar Y, Herman MJ. Overcoming shortage of pharmacists to provide pharmaceutical services in public health centers in Indonesia. Kesmas 2006; (1202):3-8. https://doi.org/10.21109/kesmas.v8i1.334
