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Efek Ekstrak Air Biji Pepaya (Carica papaya L.) terhadap Fertilitas Mencit (Mus musculus L.) Betina


 
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1. Title Title of document Efek Ekstrak Air Biji Pepaya (Carica papaya L.) terhadap Fertilitas Mencit (Mus musculus L.) Betina
 
2. Creator Author's name, affiliation, country Muhammad Feraldi Firdaus; Fakultas Sains dan Matematika Universitas Diponegoro Semarang; Indonesia
 
2. Creator Author's name, affiliation, country Agung Janika Sitasiwi; Fakultas Sains dan Matematika Universitas Diponegoro Semarang; Indonesia
 
2. Creator Author's name, affiliation, country Siti Muflichatun Mardiati; Fakultas Sains dan Matematika Universitas Diponegoro Semarang; Indonesia
 
3. Subject Discipline(s)
 
3. Subject Keyword(s) Carica papaya; anti-fertility; Mus musculus; antifertilitas
 
4. Description Abstract

Papaya seeds were known as medicinal plant which have anti-fertility potencies. So it could be used as a herbal contraceptive. The purpose of this study was to test the anti-fertility effect of Papaya seed water extract on mice (Mus musculus L.) fertility which proved by pregnancy rate, litters number and sex ratio of litters. This study was designed by Completely Randomized Design, using 15 female Swiss Webster mice that were divided into 5 treatment groups with triplicates. The K(-) group were treated by distilled water; K(+) group were treated by contraceptive pills; P1, P2, P3 groups that were treated by papaya seeds extract with 1.4, 3.5 and 7 mg/animal/day respectively. Each treatment was given orally with 0.5 ml in volume for 21 days. At the end of treatment, mice was mated. The observed parameters were pregnancies occurence, litters number and sex ratio of the litters. The litters number data were analyzed by Analysis of Variance. The results showed there was differences in pregnancy time and sex ratio between control and treatment groups, but there was not significantly different in litters number. It could be concluded that the fertility of mice was inihibited by water extract of papaya seeds.

 
5. Publisher Organizing agency, location Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2017-12-01
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier https://jurnal.ugm.ac.id/jsv/article/view/34688
 
10. Identifier Digital Object Identifier (DOI) https://doi.org/10.22146/jsv.34688
 
11. Source Title; vol., no. (year) Jurnal Sain Veteriner; Vol 35, No 2 (2017): Desember
 
12. Language English=en ind
 
13. Relation Supp. Files
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c) 2018 Jurnal Sain Veteriner
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