Case Report: The Successful Treatment of Toxocariasis in a Domestic Cat using Pyrantel Pamoate
Juni Claudia Dami(1), Luh Putu Eka Damayanti(2), Soedarmanto Indarjulianto(3*), Yanuartono Yanuartono(4), Dwi Priyowidodo(5), Agustina Dwi Wijayanti(6)
(1) Magister of Veterinary Science Faculty of Veterinary Medicine Universitas Gadjah Mada
(2) Magister of Veterinary Science Faculty of Veterinary Medicine Universitas Gadjah Mada
(3) Department of Internal Medicine Faculty of Veterinary Medicine Universitas Gadjah Mada
(4) Department of Internal Medicine Faculty of Veterinary Medicine Universitas Gadjah Mada
(5) Department of Parasitology Faculty of Veterinary Medicine Universitas Gadjah Mada
(6) Department of Pharmacology Faculty of Veterinary Medicine Universitas Gadjah Mada
(*) Corresponding Author
Abstract
Toxocariasis is an infectious disease caused by Toxocara sp. in cats that lead to deterioration of the condition and can even cause death, especially in kittens. Pyrantel pamoate is an anthelmintic that is currently being abandoned for toxocariasis. The purpose of this paper is to report the success of toxocariasis treatment in a cat using pyrantel pamoate. Female domestic cat, 3 months old, weighing 1.3 kg suffering diarrhea was used in this study. The cat examined including a physical examination, followed by laboratory examination of fecal and blood samples. The results showed the cat's body condition was thin, eye was dirty, anemic mucous membranes, dull hair/loss, and diarrhea with watery stool consistency. The cat examination revealed the presence of Toxocara sp. egg as much as 2,400 EPG in fecal sample, and the results of blood tests found that the cat had normochromic normocytic anemia. The cat was diagnosed toxocariasis with dubious prognosis. A cat treated with kaolin-pectin with 1-2 ml/kg BW orally 2 times a day for 3 days, multivitamin injection at a dose of 0.5 ml intramuscularly, and the anthelmintic pyrantel pamoate at a dose of 20mg/kg BW orally once. After 28 days of treatment, the cat was declared healthy based on better physical conditions, no diarrhea, no worm eggs in the fecal sample, and did not anemia. It concluded that cats with toxocariasis successfully cured by administering the anthelmintic pyrantel pamoate, so this drug is still recommended for the treatment of toxocariasis in cats.
Keywords
Full Text:
PDFReferences
Al Faiz, N.M. (2014). Kejadian Toksokariasis Pada Kucing di Yogyakarta Berdasarkan Pola Pemeliharaannya. Skripsi. Fakultas Kedokteran Hewan Universitas Gadjah Mada, Yogyakarta. Arion, A., Fernández-Varón, E., Cárceles, C.M., Gagyi, L., and Ognean, L. (2018). Pharmacokinetics of praziquantel and pyrantel pamoate combination following oral administration in cats. Journal of Feline Medicine and Surgery. 20(10) pp 900-904. Bijanti, R., Gandul, A.Y., dan Retno, S.W. (2010). Buku Ajar Patologi Klinik Veteriner. Surabaya: Universitas Airlangga. Bowman, D.D., Hendrix, C.H., Lindsay, D.S., and Barr, S.C. (2002). Feline Clinical Parasitology. Iowa State University Press, Ames, IA, USA. Cahyani, A.P., Suartha, I.N., dan Dharmawan, N.S. (2019). Laporan kasus: penanganan Dipylidiasis pada kucing anggora dengan Praziquantel. Jurnal Sains dan Teknologi Peternakan. 1(1): 20-24. Calista, R.M.D.P., Erawan, I.G.M.K., and Widyastuti, S.K. (2019). Laporan Kasus: Penanganan Toksokariasis dan Skabiosis pada Kucing Domestik Betina Berumur Enam Bulan. Indonesia Medicus Veterinus. 8(5) pp 660-668. Cardillo, N., Sommerfelt, I., Farina, F., Pasqualetti, M., Perez, M., Ercole, M., Rosa, A., dan Ribicich, M. (2014). A Toxocara cati eggs concentration method from cats feces, for experimental and diagnostic purposes for experimental and diagnostic purposes. Veterinary Parasitology. 56: 198-205. (CDC) Control Desease and Prevention. (2013). Parasites - Toxocariasis (Also Known As Roundworm Infection). USA. Coles, G., Jackson, F., Pomroy, W., Prichard, R., von SamsonHimmelstjerna, G., Silvestre, A., and Vercruysse, J. (2006). The detection of anthelmintic resistance in nematodes of veterinary importance. Veterinary Parasitology. 136(3–4), 167–185. Dewandaru, R.A., Indarjulianto, S., Yanuartono., Nururrozi, A., Purnamaningsih, H., dan Rusmihayati. (2019). Diare disebabkan Infeksi Escherichia coli pada Anjing. Journal of Tropical Animal and Veterinary Science. 9(2): pp 38-43. Englar, R.E. (2017). Performing The Small Animal Physical Examination. 1st ed. John Wiley & Sons, Inc. Usa. Indarjulianto, S., Yanuartono, Y., Nururrozi, A., Raharjo, S., Purnamaningsih, H., Widiyono, I., Hartati, S., Dami, J.C., and Damayanti, L.P. (2022). Study of Digestive Tract Diseases in Cats. In7th International Conference on Biological Science (ICBS 2021) pp. 494-497. Atlantis Press. Joy, A.T., Chris, O.I., and Godwin, N.C. (2017). Toxocariasis and Public Health: An Epidemiological Review. Glob. J. Infect. Dis. Clin. Res. 3, 28–39. Katzung, B.G. (1998). Farmakologi Dasar dan Klinik Edisi VIII. Jakarta : EGC. pp : 857–837. Kusnoto. (2005). Prevalensi toksokariasis pada kucing liar di Surabaya melalui bedah saluran pencernaan. Media Kedokteran Hewan. 21(1):7-11. Lee, A.C.Y., Schantz, P.M., Kazacos, K.R., Montgomery, S.P., and Bowman, D.D. (2010). Epidemiologic and zoonotic aspects of ascarid infections in dogs and cats. Trends in Parasitology. 26(4): 155–161. Manurung, R.S. dan Lambok, S. (2012). Infeksi Toxocara sp. pada hewan peliharaan di Kelurahan Padang Bulan tahun 2012. EJournal. Fakultas Kedokteran USU. 1(1):1-3. Murniati, S.E. dan Ridwan, Y. (2016). Prevalensi dan Faktor Risiko Infeksi Toxocara cati pada Kucing Peliharaan di Kota Bogor. Program Studi Kesehatan Masyarakat Veteriner Program Pascasarjana Fakultas Kedokteran Hewan Institut Pertanian Bogor. Bogor. Nealma, S., Dwinata, I.M., dan Oka, I.B.M. (2013). Prevalensi infeksi cacing Toxocara cati pada kucing lokal di wilayah Denpasar. J. Indo. Med. Vet. 2(4):428-436. Overgaauw, P.A. (1997). Aspect of Toxocara epidemiology: Toxocariasis in dogs and cats. J. Parasitol. 23(3):215-231. Overgaauw, P.A.M. and Knapen, F.V. (2013). Veterinary and public health aspect of Toxocara spp. Vet. Parasitol. 193 (4): 398-403. Palmer, C.S., Rebecca, J.T., Ian, D.R., Rusell, P.H., Aileen, E., Lyndon, W., Robert, R., and Andrew, T. (2007). The veterinary and public significance of hookworm in dogs and cats in Australia and the status of A.ceylanicum. Vet. Parasitol. 145:304-313. Panova, O., Khrustalev, A., Sysoeva, N., Baranova, M., Glamazdin, I., and Kryukovskaya, G. (2021). Standard Blood Tests Indicate Changes of Toxocariasis in Carnivores. International research conference on Challenges and Advances in Farming, Food Manufacturing, Agricultural Research and Education. KnE Life Sciences. pp 501–510. Papich, M.G. (2010). Saunders Handbooks of Veterinary Drugs Small and Large Animal Third Edition. Elsevier: USA. 252-253, 596-598. Plumb, C.D. (2008). Veterinary Drugs Handbook. 6th Ed. Minesota(US): Wiley, John and Sons. Roeswandono., Mussa, O.R.P.A., Pangaribuan, M.J.A., dan Palgunadi, B.U. (2019). Perhitungan Telur Toxocara cati dan Jumlah Sel Darah Putih pada Kucing Liar (Felis catus) di Dukuh Kupang Surabaya. Jurnal Vitek Bidang Kedokteran Hewan. 9: 18-23. Salasia, S.I.O., dan Hariono, B. (2014). Patologi Klinik Veteriner. Samudra Biru. Yogyakarta. Sariego, I., Kanobana, K., Rojas, L., Speybroeck N., Polman K., and Nunez, F.A. (2012). Toxocariasis in Cuba : A literature Review. PMC journal. Plos Neglected Tropical Disease: vol. 6. Sheikh, M.M., Tak, H., and Fazili, M.F. (2020). Gastrointestinal Helminths of Cat (Felis catus) In Kashmir Valley, India. International Journal Of Scientific and Technology Research. 9: 314-319. Soeharsono. (2007). Penyakit Zoonotik pada Anjing dan Kucing. Yogyakarta (ID): Kanisius Press. Supraptini, J. (2013). Kasus Toxocariasis pada Anjing di Rumah Sakit Hewan Pendidikan Universitas Airlangga. Jurnal Klinik Veteriner. 2 (1). Suroiyah, F.A., Hastutiek, P., Yudhana, A., Sunarso, A., Purnama, M.T.E., dan Praja, R.N. (2018). Prevalensi Infeksi Toxocara cati pada Kucing Peliharaan di Kecamatan Banyuwangi. Jurnal Medik Veteriner. 1(3) p 99. Tilley, L.P., and Smith, F.W.K. (2011). Wiley-Blackwell’s Five-Minute Veterinary Consult: Canine and Feline. Wiley-Blackwell. USA. Widodo, S., Sajuthi, D., Choliq, C., Wijaya, A., Wulansari, R., dan Lelana, R.P.A. (2011). Diagnostik Klinik Hewan Kecil. Bogor (ID) : IPB Press. Wijaya, J.S. (2017). Perbandingan Efektivitas dan Efek Samping Albendazole dengan Kombinasi Mebendazole-Pyrantel Pamoat Untuk Terapi Soil-transmitted Helminthiasis Anak Sekolah Dasar Kecamatan Medan Tembung. CDK. 44(6): 253. Wuhan, Y.O.P. (2019). Diagnosa Klinis, Hematologi, Molekuler Ehrlichiosis dan Karakterisasi Gen glta Ehrlichia canis pada Pasien Anjing di Yogyakarta. Thesis. Fakultas Kedokteran Hewan. Universitas Gadjah Mada.
DOI: https://doi.org/10.22146/jsv.79940
Article Metrics
Abstract views : 1507 | views : 2114Refbacks
- There are currently no refbacks.
Copyright (c) 2023 Jurnal Sain Veteriner
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Jurnal Sain Veteriner Indexed by
Copyright of JSV (Jurnal Sain Veteriner) ISSN 0126-0421 (print), ISSN 2407-3733 (online).
Fakultas Kedokteran Hewan, Universitas Gadjah Mada
Jl. Fauna No.2, Karangmalang, Yogyakarta
Phone: 0274-560862
Fax: 0274-560861
Email: jsv_fkh@ugm.ac.id
HP. 0895363078367
Jurnal Sain Veteriner is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
View My Stats