Pemilihan Antibiotika pada Anjing Diare yang Terinfeksi Escherichia coli

https://doi.org/10.22146/jsv.60327

Soedarmanto Indarjulianto(1*), Sitarina Widyarini(2), Gede Bayu Suparta(3), Alfarisa Nurrurozi(4), Yanuartono .(5), Slamet Raharjo(6), Yeremia Yobelino Sitompul(7), Ika Tidariani(8), Anna Ekawati(9), Mega Cahya Nalasukma(10)

(1) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(2) Departemen Patologi Fakultas Kedokteran Hewan Universitas Gadjah Mada
(3) Departemen Fisika Fakultas MIPA Universitas Gadjah Mada
(4) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(5) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(6) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(7) Departemen Klinik, Reproduksi, Patologi dan Nutrisi Fakultas Kedokteran Hewan Universitas Nusa Cendana, Kupang
(8) Klinik Hewan Calico Yogyakarta
(9) Klinik Hewan Griya Satwa Lestari Semarang
(10) Klinik Hewan Kayu Manis Yogyakarta
(*) Corresponding Author

Abstract


Diare adalah penyakit yang sering ditemukan pada anjing dan Escherichia coli merupakan salah satu yang dianggap sebagai penyebabnya. Tujuan dari penelitian ini adalah menentukan diagnosis diare pada anjing yang disebabkan E. coli dan menentukan pilihan antibiotika sebagai terapi utama. Sebanyak 3 pasien anjing diare digunakan di dalam penelitian ini. Semua anjing diperiksa secara fisik dan E. coli diidentifikasi dari sampel fesesnya. Sampel feses dipupuk pada agar Harlequin™ E. coli/Coliform Medium dan diinkubasi pada 37 °C selama 24 jam. Koloni yang tumbuh diamati, dicat Gram dan diperiksa di bawah mikroskop. Bakteri selanjutnya diuji sensitivitasnya terhadap amoxicillin, chloramphenicol, doxycycline dan enrofloxacin menggunakan metode disk difusi. Zona pertumbuhan bakteri diukur dan dibandingkan dengan standar. Hasil penelitian menunjukkan bahwa E. coli ditemukan pada semua (3) sampel feses anjing diare. Semua bakteri tersebut sensitif terhadap chloramphenicol dan 1 isolat sensitif terhadap amoxicillin, tetapi isolat lainnya berifat intermedier sampai resisten terhadap amoxicillin, doxycylin dan enrofloksasin. Kesimpulan penelitian ini adalah E. coli dapat berperan sebagai penyebab diare  pada anjing dan chloramphenicol adalah antibiotika pilihan utama untuk terapi.

Keywords


anjing; diarrhea; Escherichia coli; resistensi antibiotika; Chloramphenicol

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References

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DOI: https://doi.org/10.22146/jsv.60327

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