The Efficacy Study of Duramectin, Oxfendazole, Piperazine, and Pyrantel pamoate Against Gastrointestinal Worms In Horses In Yogyakarta Special Region*)

https://doi.org/10.22146/jsv.42969

yuriadi yuriadi(1*), Ida Tjahajati(2), Soedarmanto Indarjulianto(3), Irkham Widiyono(4)

(1) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(2) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(3) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(4) Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
(*) Corresponding Author

Abstract


ABSTRACT

 

This research aimed at determining the efficacy of duramectin, oxfendazole, piperazine, and pyrantelpamoate against gastrointestinal worms in horses in Yogyakarta Special Region and Central Java. The object of research involved 40 horses diagnosed with gastrointestinal worm infection. Prior to the research, all of the horses were subjected to examination for clinical symptoms and parasitology laboratory checkup for signs of worm eggs in their feces, and they were pronounced positive for experiment animals with at least 150 eggs per gram of feces per horse. The research horses were weighed to determine the dose of worm medication to be used. The research horses are divided into four treatment groups, each group consists of ten horses. Group I was given duramectin with a dose of 0.2 mg/kg of body weight. Group II was given oxfendazole with a dose of 7.5 mg/kg of body weight, Group III was given 125 mg Piperazin treatment per kilogram of body weight and Group IV was given pyrantelpamoate with a dose of 20 mg/kg of body weight. After receiving themedication, the horses were observed to document the progress in terms of clinical symptoms and the amount and type of worm eggs in their feces every three days for four times in a row. The research data results were tabulated and were descriptive-comparatively analyzed.

The research result showed varying efficacy level of worm medication for horses. Oxfendazole kills Strongylus and Parascaris worms. Duramectin kills Strongylus worms and reduce some of the Parascaris worms. Piperazineandpyrantelpamoate kills the Strongylus wormsand reduce some of the Parascaris.

 

Keywords: horses, gastrointestinal worms, Duramectin, Oxfendazole, Piperazine, PyrantelPamoate.

 

 


Keywords


horses, gastrointestinal worms, Duramectin, Oxfendazole, Piperazine, PyrantelPamoate.

Full Text:

PDF


References

Anonymous, 2012. Laporan Tahunan Klinik Hewan Keliling PORDASI DIY danJawa Tengah. Adams, R. H., 1995.Veterinary Pharmacology and Therapeutic, 7th Edition. Iowa StateUniversity Press. Ames. Blood, D. C., danHanderson, J. A., 1989. Veterinary Medicine 5th Edition. Lea and Febiger, Pliladelphia.Pp. 767-768. Brander, G. C. dan Pugh, D. M., Bywater, R.I., dan Jenkins, W.L., 1991.VeterinaryApplied Pharmacology and Therapeutics, 5th Edition.BailliereTindall, British. Duncan, J., 1983. Anthelmintics for Use in Equine Practice. Pharmacological Basis of Large Animal Medicine Eds. Bogan, J. A., et al. Blackwell Scientific Publication. Oxford. Frasser, C. M., 2005. The Merck Veterinary Manual: a Handbook of Diagnosis, Therapy, and Disease. Blackwell Publishing. USA. Ganiswarna, Sulistia G.,1995. Farmakologi dan terapi, Edisi keempat. Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia. Jakarta. Gordon, L. C., Edward, H., Walter, E. W., Glen, J. S., dan Richard, B. K., 1981. Formulary. Purdue University School of Veterinary Medicine. Katzung, B. G., 2004. Farmakologi Dasar dan Klinik. Bagian Farmakologi Fakultas Kedokteran Universitas Airlangga. Kirk, R.W., Bistner, S.I. 1985. Hand book of Veterinary Procedures and Emergency Treatment. 4th Ed. W.B. Saunders Co. Philadelphia. P 928. Levine, N. D., 1968. Nematoda Parasites of Domestic Animals and Man. Burgess Publishing Company. Minneapolis. Hal. 185-189. Levine, N. D., 1994. Parasitologi Veteriner. Gadjah Mada University Press. Mutschler, E., 1991, Dinamika Obat. ITB Bandung. Radostits, O. M., Gay, C. C., Hinchcliff, K. W., Constable. P. D., 2006. Veterinary Medicine a Textbook of the Disease of Cattle, Horses, Sheep, Pigs and Goat 10th Ed. Saunders Elsevier. USA. Rosoff, L. S., 1990. Handbook of Veterinary Drugs 2nd Ed. Springer Publisher Company. New York. Soulsby, E.J.L., 1982. Helminth, Anthropods and Protozoa of Domesticated Animal. 7th ed.ELSB and Bailliere Tindal, London. Hal. 313-314. Subronto, P. danTjahayati, I., 2001. IlmuPenyakitTernak II. Gadjah Mada University Press, Yogyakarta. Hal. 397-399. Tanu, I., 1972.Anthelmintika dalam Farmakologi dan Terapi, Bagian Farmakologi, FKUI, Jakarta. Yordan, H. E. dan Ewing, S. A., 1980. Concepts of Gastro-intestinal Parasitism and Strategies for Designing Corrective and Control Programs.Veterinary Gastroenterology Ed. Anderson, N. V. Lea and Febiger. Philadelphia.



DOI: https://doi.org/10.22146/jsv.42969

Article Metrics

Abstract views : 222 | views : 178

Refbacks

  • There are currently no refbacks.




Copyright (c) 2019 Jurnal Sain Veteriner

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Jurnal Sain Veteriner Indexed by

    CrossrefROADCOREDimensions  JournalTOCs   


Copyright of JSV (Jurnal Sain Veteriner) ISSN 0126-0421 (print), ISSN 2407-3733 (online).

Fakultas Kedokteran Hewan, Universitas Gadjah Mada

Jl. Fauna No.2, Karangmalang, Yogyakarta

Phone: 0274-560862

Fax: 0274-560861

Email: jsv_fkh@ugm.ac.id

Jurnal Sain Veteriner is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

 

free
web stats View My Stats