PERBEDAAN EFEKTIVITAS TOPIKAL GEL ASAM HIALURONAT DAN GEL METRONIDAZOL TERHADAP PENYEMBUHAN JARINGAN PERIODONTAL SETELAH KURETASE PADA PERIODONTITIS KRONIS

Abstract

Periodontitis is an infl ammation on the  supporting tissues of the teeth. Curettage is a procedure in the treatment of periodontitis. Hyaluronic acid has bacteriostatic effect, anti-infl ammatory, increases proliferation, metabolism, and cell migration. Metronidazole effective for an areob sub-gingival bacteria that contribute to  periodontitis. This study aimed to determine differences in the effectiveness of topical hyaluronic acid gel and metronidazole gel on periodontal tissue healing after curettage in chronic periodontitis.
Subjects were patients with chronic periodontitis with 4-6 mm periodontal pocket depth. Study divided into 2 groups: topical hyaluronic acid gel and metronidazole gel, each group with 15 periodontal pockets. Retrieval data
PD, CAL and BOP on days 0 and 21st. Curettage and topical application of hyaluronic acid gel and metronidazole gel according to treatment group performed on day 0. Data PD and CAL  were analyzed by Mann Whitney test and BOP was tested by Chi Square.
The results showed a mean reduction PD in  hyaluronic acid gel group larger than metronidazole gel group (1,27:0,75). The mean reduction  CAL in hyaluronic acid gel group larger than metronidazole gel group (1,06:0,67). Loss of BOP hialuronat  acid gel group larger than metronidazole gel group (14:12). Statistical tests in both treatment groups showed the results of p < 0.05, which means there is a signifi cant difference in the reduction in PD , CAL and  loss of BOP. The conclusion of this study is topical hyaluronic acid gel more effective in the healing of periodontal tissues than metronidazole gel after curettage in chronic periodontitis.