Pengaruh pemberian jelly mengandung glukomanan porang (Amorphophalus oncophyllus) dan inulin sebagai makanan selingan terhadap berat badan, IMT, lemak tubuh, kadar kolesterol total, dan trigliserida pada orang dewasa obesitas

https://doi.org/10.22146/ijcn.58343

Rissa Saputri(1), Rizka Qurrota A’yun(2), Emy Huriyati(3), Lily Arsanti Lestari(4), Sri Rahayoe(5), Yusmiati Yusmiati(6), Okta Haksaica Sulistyo(7), Eni Harmayani(8*)

(1) Departemen Biostatistika, Epidemiologi, dan Kesehatan Populasi, Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia
(2) Departemen Biostatistika, Epidemiologi, dan Kesehatan Populasi, Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia
(3) Departemen Gizi dan Kesehatan, Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia
(4) Departemen Gizi dan Kesehatan, Fakultas Kedokteran, Kesehatan Masyarakat, dan Keperawatan, Universitas Gadjah Mada, Yogyakarta, Indonesia / Institute for Halal Industry & System, Universitas Gadjah Mada, Yogyakarta, Indonesia
(5) Departemen Teknik Pertanian dan Biosistem, Fakultas Teknologi Pertanian, Universitas Gadjah Mada, Yogyakarta, Indonesia
(6) Rumah Sakit Akademik, Universitas Gadjah Mada, Yogyakarta, Indonesia
(7) Rumah Sakit Akademik, Universitas Gadjah Mada, Yogyakarta, Indonesia
(8) Departemen Teknologi Pangan dan Hasil Pertanian, Fakultas Teknologi Pertanian, Universitas Gadjah Mada, Yogyakarta, Indonesia
(*) Corresponding Author

Abstract


Effect of jelly containing of porang (Amorphophalus oncophyllus) glucomannan and inulin as a snack to the body weight, BMI, body fat, total cholesterol, and triglyceride levels in obese adult


Background: Obesity is a major risk factor for noncommunicable diseases, especially cardiovascular disease. Porang glucomannan and inulin are water-soluble fibers that have been widely studied for their health benefits. Jelly products that contain both types of fiber are expected to have the ability to support the diet program in adults with obese nutritional status.

Objective: To determine the effect of giving jelly containing a combination of glucomannan porang and inulin on body weight, BMI, body fat, total cholesterol, and triglyceride levels in obese adults.

Methods: This research is a randomized controlled trial using a pre and post-test design. A total of 55 subjects who live in the Special Region of Yogyakarta, participated in the study until the end of 8 weeks. Subjects were divided into 3 groups; 18 people in the group who were given jelly containing glucomannan porang and inulin (porang-inulin jelly group), 17 people in the group who were given placebo jelly (placebo jelly group), and 20 people in the negative control group who did not get jelly (negative control group). All subjects received a low-calorie diet intervention of 1,500 kcal in the first month and 1,200 kcal in the second month.

Results: There was a significant reduction in body weight and BMI (p<0.05) in all groups, but there was no difference in the effect between the porang–inulin jelly group and the other groups (p>0.05). Clinically, there was a significant decrease in body fat percentage in the porang-inulin jelly group, in subjects with the category of an excess fat percent (-0.90 ± 0.49%) and obesity (-1.48 ± 0.83%). A significant decrease in fat percentage also occurred in the porang-inulin jelly group, both in male subjects (-1.42 ± 0.50%) and female (-1.15 ± 0.82%), while in the placebo jelly group and negative control, the decrease did not occur in all categories and genders. There was an increase in total cholesterol levels in the negative control group (p<0.05) after the study (+7.45 ± 13.18 mg/dL). In the porang-inulin jelly group, the increase in cholesterol levels did not occur significantly either in general or based on clinical categories and gender.

Conclusion: Consumption of porang-inulin jelly may support weight loss programs, BMI, percent body fat, and inhibit the increase of total cholesterol and triglyceride levels in adults with obese nutritional status.


Keywords


body mass index; body weight; fat percent; inulin; obesity; Porang glucomannan; total cholesterol level; triglycerides

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References

  1. World Health Organization. Obesity: Preventing and managing the global epidemic. Geneva: WHO Technical Report Series; 2000.
  2. Kemenkes. Hasil utama Riskesdas 2018. Jakarta: Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia; 2018.
  3. Romieu I, Dossus L, Barquera S, Blottière HM, Franks PW, Willett WC, et al. Energy balance and obesity: what are the main drivers ?’. Cancer Causes & Control. 2017;28(3):247-58. doi: 10.1007/s10552-017-0869-z
  4. Forslund B, Torgerson JS, Sjöström L, Lindroos AK. Snacking frequency in relation to energy intake and food choices in obese men and women compared to a reference population. Int J Obes (Lond). 2005;29(6):711-9. doi: 10.1038/sj.ijo.0802950
  5. Graaf C de. Effects of snacks on energy intake: an evolutionary perspective. Appetite. 2006;47(1):18-23.doi: 10.1016/j.appet.2006.02.007
  6. Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev. 2010;15(1):68-75.
  7. Harmayani E, Aprilia V, Marsono Y. (2014). Characterization of glucomannan from Amorphophallus oncophyllus and its prebiotic activity in vivo. Carbohydr Polym. 2014;112:475-9. doi: 10.1016/j.carbpol.2014.06.019
  8. Kasno A. Iles-Iles umbi-umbian potensial sebagai tabungan tahunan. Buletin Palawija. 2008;20(15):15-20.
  9. Kaats GR, Bagchi D, Preuss HG. Konjac glucomannan dietary supplementation causes significant fat loss in konjac glucomannan dietary supplementation causes significant fat loss in compliant overweight adults. J Am Coll Nutr. 2015;1-7. doi: 10.1080/07315724.2015.1009194
  10. Behera SS, Ray RC. Konjac glucomannan, a promising polysaccharide of Amorphophallus konjac K. Koch in health care. International Journal of Biological Macromolecules. 2016;92:942-56. doi: 10.1016/j.ijbiomac.2016.07.098
  11. Wu W, Yang L, Chen H. Effects of konjac glucomannan, inulin and cellulose on acute colonic responses to genotoxic azoxymethane. Food Chem. 2014;155:304-10. doi: 10.1016/j.foodchem.2014.01.065
  12. Delzenne NM, Kok N. (2001) Effects of fructans-type prebiotics on lipid metabolism. Am J Clin Nutr. 2001;73(2 Suppl):456S-458S. doi: 10.1093/ajcn/73.2.456s
  13. Delzenne NM, Cani PD, Daubioul C, Neyrinck AM. Impact of inulin and oligofructose on gastrointestinal peptides. Br J Nutr. 2005;93 Suppl 1:S157-61. doi: 10.1079/bjn20041342
  14. Njike VY, Kavak Y, Treu JA, Doughty K, Katz DL. Snacking, satiety, and weight: a randomized, controlled trial. Am J Health Promot. 2017;31(4):296-301. doi: 10.4278/ajhp.150120-QUAN-676
  15. Piehowski KE, Preston AG, Miller DL, Nickols-Richardson SM. A reduced-calorie dietary pattern including a daily sweet snack promotes body weight reduction and body composition improvements in premenopausal women who are overweight and obese: a pilot study. J Am Diet Assoc. 2011;111(8):1198-203. doi: 10.1016/j.jada.2011.05.013
  16. Barnes TL, French SA, Harnack LJ, Mitchell NR, Wolfson J. Snacking behaviors, diet quality, and body mass index in a community sample of working adults. J Acad Nutr Diet. 2015;115(7):1117-23. doi: 10.1016/j.jand.2015.01.009
  17. Njike VY, Kavak Y, Treu JA, Doughty K, Katz DL. Snacking, satiety, and weight: a randomized, controlled trial. Am J Health Promot. 2017;31(4):296-301. doi: 10.4278/ajhp.150120-QUAN-676
  18. World Health Organization. The Asia-Pacific perspective : redefining obesity and its treatment. Geneva: WHO; 2000.
  19. Sood N, Baker WL, Coleman CI. Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: systematic review and meta-analysis. Am J Clin Nutr. 2008;88(4):1167-75. doi: 10.1093/ajcn/88.4.1167
  20. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr. 1999;129(7 Suppl):1471S-3S. doi: 10.1093/jn/129.7.1471S
  21. Genta S, Cabrera W, Habib N, Pons J, Carillo IM, Sánchez S, et al. Yacon syrup: beneficial effects on obesity and insulin resistance in humans. Clin Nutr. 2009;28(2):182-7. doi: 10.1016/j.clnu.2009.01.013
  22. Sanchez M, Darimont C, Panahi S, Drapeau V, Marette A, Tremblay A, et al. Effects of a diet-based weight-reducing program eating behaviour traits , and psychosocial behaviours in obese individuals. Nutrients. 2017;9(3):284. doi:10.3390/nu9030284
  23. Birketvedt GS, Shimshi M, Thom E, Florholmen J. Experiences with three different fiber supplements in weight reduction. Med Sci Monit. 2005 Jan;11(1):PI5-8.
  24. Liber A, Szajewska H. Effects of inulin-type fructans on appetite, energy intake, and body weight in children and adults: systematic review of randomized controlled trials. Ann Nutr Metab. 2013;63(1-2):42-54. doi: 10.1159/000350312
  25. Binks M, Neil PMO. Referral sources to a weight management program: relation to outcome. J Gen Intern Med. 2002;17(8):596-603. doi: 10.1046/j.1525-1497.2002.11028.x
  26. Sáez Belló M, Segarra Villalba C, Gras Colomer E, Frias Ruiz P, Climente Marti M. Effectiveness and safety of very low calory diets in obese patients. Am J Clin Nutr. 2002;75(6):1017-22. doi: 10.7399/FH.2014.38.1.978
  27. Parigi A Del, Chen K, Gautier JF, Salbe AD, Pratley RE, Antonio Tataranni P, et al. Sex differences in the human brain’s response to hunger and satiation. American Journal of Clinical Nutrition, 75: 1017–1022. doi: 10.1093/ajcn/75.6.1017
  28. Gregersen NT, Møller BK, Raben A, Kristensen ST, Holm L, Astrup A, et al. Determinants of appetite ratings: the role of age, gender, BMI, physical activity, smoking habits, and diet/weight concern. Food Nutr Res. 2011;55. doi: 10.3402/fnr.v55i0.7028
  29. Bédard A, Hudon AM, Drapeau V, Corneau L, Dodin S, Lemieux S. Gender differences in the appetite response to a satiating diet. Journal of Obesity. 2015. doi: 10.1155/2015/140139
  30. Cani PD, Lecourt E, Dewulf EM, Sohet FM, Pachikian BD, Delzenne NM, et al. Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. Am J Clin Nutr. 2009;90(5):1236-43. doi: 10.3945/ajcn.2009.28095
  31. Parnell JA, Reimer RA. Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults. Am J Clin Nutr. 2009;89(6):1751-9. doi: 10.3945/ajcn.2009.27465
  32. Pal S, Ho S, Gahler RJ, Wood S. Effect on body weight and composition in overweight / obese Australian adults over 12 months consumption of two different types of fibre supplementation in a randomized trial. Nutr Metab (Lond). 2016 Nov 17;13:82. doi: 10.1186/s12986-016-0141-7
  33. Guess ND, Dornhorst A, Oliver N, Bell JD, Thomas EL, Frost GS. A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutr Metab (Lond). 2015;12:36. doi: 10.1186/s12986-015-0033-2
  34. El-Zayat SR, Sibaii H, El-Shamy KA. Physiological process of fat loss. Bulletin of the National Research Centre. 2019;43:208. doi: 10.1186/s42269-019-0238-z
  35. Tala Z. Manfaat serat bagi kesehatan. Sumatera: Universitas Sumatera Utara; 2019.
  36. Kasubuchi M, Hasegawa S, Hiramatsu T, Ichimura A, Kimura I. Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation. Nutrients. 2015;7(4):2839-49. doi: 10.3390/nu7042839
  37. Kumar M, Nagpal R, Kumar R, Hemalatha R, Vermaet V, Yadav H, et al. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. Exp Diabetes Res. 2012;2012:902917. doi: 10.1155/2012/902917
  38. Wood RJ, Fernandez ML, Sharman MJ, Silvestre R, Greene CM, Volek JS, et al. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber on plasma low-density lipoprotein cholesterol and other clinical markers of cardiovascular risk. Metabolism. 2007;56(1):58-67. doi: 10.1016/j.metabol.2006.08.021
  39. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 1995;61(3):585-9. doi: 10.1093/ajcn/61.3.585
  40. Dehghan P, Gargari BP, Asgharijafarabadi M. Effects of high performance inulin supplementation on glycemic status and lipid profile in women with type 2 diabetes: a randomized, placebo-controlled clinical trial. Health Promot Perspect. 2013;3(1):55-63. doi: 10.5681/hpp.2013.007
  41. Causey JL, Feirtag JM, Gallaher DD, Tungland BC, Slavin JL, et al. Effects of dietary inulin on serum lipids, blood glucose and the gastrointestinal environment in hypercholesterolemic men. Nutrition Research. 2000;20(2):191-201. doi: 10.1016/S0271-5317(99)00152-9
  42. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr. 1999;129(7 Suppl):1471S-3S. doi: 10.1093/jn/129.7.1471S
  43. Balcázar-Muñoz BR, Martínez-Abundis E, González-Ortiz, M. Effect of oral inulin administration on lipid profile and insulin sensitivity in subjects with obesity and dyslipidemia. Rev Med Chil. 2003;131(6):597-604.
  44. Tovar AR, Caamaño MC, Garcia-Padilla S, García OP, Duarte MA, Rosado JL. The inclusion of a partial meal replacement with or without inulin to a calorie restricted diet contributes to reach recommended intakes of micronutrients and decrease plasma triglycerides: a randomized clinical trial in obese Mexican women. Nutr J. 2012;11:44. doi: 10.1186/1475-2891-11-44
  45. Jeppesen J, Schaaf P, Jones C, Zhou MY, Chen YD, Reaven GM. Effects of low-fat, high-carbohydrate diets on risk factors for ischemic heart disease in postmenopausal women. Am J Clin Nutr. 1997;65(4):1027-33. doi: 10.1093/ajcn/65.4.1027
  46. Hannon BA, Thompson SV, Edwards CG, Skinner SK, Niemiro GM, Khan NA, et al. Dietary fiber is independently related to blood triglycerides among adults with overweight and obesity. Curr Dev Nutr. 2018;3(2):nzy094. doi: 10.1093/cdn/nzy094
  47. Kaur N, Gupta AK. Applications of inulin and oligofructose in health and nutrition. J Biosci. 2002;27(7):703-14. doi: 10.1007/BF02708379
  48. Chambers ES, Viardot A, Psichas A, Morrison DJ, Murphy KG, Frost G, et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults. Gut. 2015;64:1744-54. doi: 10.1136/gutjnl-2014-307913
  49. PERKENI. Konsensus pengelolaan dan pencegahan diabetes melitus tipe 2 di Indonesia. Jakarta: Perkumpulan Endrokinologi Indonesial; 2015.
  50. McClung HL, Champagne CM, Allen HR, McGraw SM, Young AJ, Crombie AP, et al. Digital food photography technology improves efficiency and feasibility of dietary intake assessments in large populations eating ad libitum in collective dining facilities. Appetite. 2017;116:389-94. doi: 10.1016/j.appet.2017.05.025



DOI: https://doi.org/10.22146/ijcn.58343

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