Acute Coronary Syndrome in Young Patients at Dr. Sardjito General Hospital

Budi Yuli Setianto; Julia Sari; Anggoro Budi Hartopo; Putrika Prastuti Ra Gharini

doi:10.22146/acta interna.5728

Acute Coronary Syndrome in Young Patients at Dr. Sardjito General Hospital

https://doi.org/10.22146/acta%20interna.5728

Budi Yuli Setianto^(1*), Julia Sari⁽²⁾, Anggoro Budi Hartopo⁽³⁾, Putrika Prastuti Ra Gharini⁽⁴⁾

(1)
(2)
(3)
(4)
(*) Corresponding Author

Abstract

ABSTRACT
Background: The incidence of acute coronary syndrome in the young patients is increased recently. Several studies reported that young patients have distinct clinical characteristics as compare with older patients.
Objective: To assess the prevalence, risk factors and clinical presentation of acute coronary syndrome(ACS) in young patients at Dr. Sardjito Hospital, Yogyakarta.
Methods: We conducted a cross sectional study between September 2008-May 2009 at intensive cardiovascular care unit (ICCU) of Dr. Sardjito Hospital. We enrolled consecutive patients admitted with acute coronary syndrome. We divided the patients as young ACS (age ≤ 45 years) and older ACS (age >45 years). We compared cardiovascular risk factors, clinical presentation and clinical spectrums from both groups. Statistics analysis was performing using chi-square test, p value < 0.05 was considered significantly different.
Results: In our study there were 20 (13.5%) young ACS and 128 (86.5%) older ACS patients. Most young ACS patients are male (90%). Proportion of diabetes mellitus in young ACS was not different from that in older ACS patients (20% vs. 18.8%; p=0.55). Hypertension was not different either (50% vs. 53.1%; p=0.49). Sixty percent of young ACS patients were smoker, however its proportion did not differ from older ACS patients (p=0.84). There were no signifi cant differences of dyslipidemia. The young ACS patients mostly experienced STEMI than NSTEMI and unstable angina (55% vs. 15% vs. 30%), but there were no signifi cant differences when compared to older ACS patients (p=0.65). Thirty percent of young ACS patients presented with Killip class II or higher, however there were no significant differences between groups (p=0.40).
Conclusion: In this study we found that there were no signifi cant differences in risk factors, clinical presentation and spectrums between young ACS and older ACS patients. The need for prevention program in both groups should not be difference.
Keywords: ACS– young– older– clinical presentation.

Full Text:

PDF

References

REFERENCES

Rosengren A, Wallentin L, Simoons M, Gitt AK, Behar S, Battler A, Hasdai D. Age, clinical presentation, and outcome of acute coronary syndromes in the Euroheart acute coronary syndrome survey. Eur Heart J 2006;27:789-795.

Schoenenberger AW, Radovanovic D, Stauffer J-C, Windecker S, Urban P, Niedermaier G, Keller P-F, Gutzwiller F, Erne P. Acute coronary syndromes in young patients: Presentation, treatment and outcome. Int J Cardiol 2011;148:300- 304.

Lu HT, Nordin RB. Ethnic differences in the occurrence of acute coronary syndrome: results of the Malaysian National Cardiovascular Disease (NCVD) Database Registry (March 2006 - February 2010). BMC CardiovascDisord2013;13(1):97

Srimahachota S, Kanjanavanit R, Boonyaratavej S, Boonsom W, Veerakul G, Tresukosol D. Demographic, management practices and in-hospital outcomes of Thai Acute Coronary Syndrome Registry (TACSR): the difference from the Western world. J Med Assoc Thai 2007;90:Suppl1:1-11.

Avezum A, Makdisse M, Spencer F, Gore M, Fox KA, Montalescot G, Eagle KA, White K, Mehta RH, Knobel E, Collet JP. Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE). Am Heart J2005;149(1):67-73.

Tungsubutra W, Tresukosol D, Buddhari W, Boonsom W, Sanguanwang S, Srichaiveth B. Acute coronary syndrome in young adults: The Thai ACS registry. J Med Assoc Thai 2007; 90 :Suppl 1: 81-90.

Morillas P, Bertomeu V, Pabón P, Ancillo P, Bermejo J, Fernández C, Arós F. Characteristics and outcome of acute myocardial infarction in young patients. The PRIAMHO II study. Cardiology 2007;107(4):217-225.

Panduranga P, Sulaiman K, Al-Zakwani I, Abdelrahman S. Acute coronary syndrome in young adults from Oman: Result from the Gulf Registry of acute coronary events. Heart Views 2010;11(3):93-98.

Sumartono W, Sirait AM, Holy M, Thabrany H. Smoking and socio-demographic determinant of cardiovascular diseases among males 45+ years in Indonesia. Int J Environ Res Public Health 2011:8:528-539.

Kosen S, Hardjo H, Kadarmanto, Sinha DN, Palipudi KM, Wibisana W, Tarigan I. Global Adult Tobacco Survey: Indonesia Report 2011. 2012. New Delhi: World Health Organization, Regional Office for South East Asia.

DOI: https://doi.org/10.22146/acta%20interna.5728