The Effect of Kayu Akway (Drymis sp) Extract on The Number of Leukocyte of The Male Mice (Mus musculus L)

Abstract

Kayu Akway (Drymis sp) is an endemic herb plant in West Papua. Akway plant is a plant traditionally used by Papua citizen for various bene ts, such as increasing endurance and durability, vitality, controlling birth range, and also curing kudis. The objective of this research was to determine the effect of Kayu Akway extract on the number of leukocyte of male mice (Mus musculus L). The experimental method used in this research is randomized complete design with 3 blocks of treatments and 4 times repetition with given orally for two weeks. The block of treatments are control (K), dose of oral 1.3 ml/kg body weight (K1), and dose of oral 3.3 ml/kg body weight (K2). The data of leukocyte number is analyzed by Analysis of Variance (ANOVA) and then continued by Duncan Multiple Range Test at 95% con dence interval. The result showed that statistically insigni cant number of leukocyte in K1 and K2 treatment when compared with control. In the contrary, the lowest leukocyte number was found in the control treatment that was untreated with oral extract. While increased the number of leukocyte was found in the K1 treatment and the highest leukocyte number was found in the K2 treatment. It concluded that seen a trend increase in the number of leukocyte on the second dose compared to control.