Effect of Pre-Treatment Phase, Treatment Phase, and Recovery Phase on Fibrinogen Levels in FMD Cattle Cases

Sarmin Sarmin

doi:10.22146/ijvs.v3i2.83073

Effect of Pre-Treatment Phase, Treatment Phase, and Recovery Phase on Fibrinogen Levels in FMD Cattle Cases

https://doi.org/10.22146/ijvs.v3i2.83073

Sarmin Sarmin^(1*)

(1) Fakultas Kedokteran Hewan Universitas Gadjah Mada, Yogyakarta
(*) Corresponding Author

Abstract

This study was conducted to determine whether there is an influence between the pre-treatment phase, treatment phase, and recovery phase on fibrinogen levels in cows infected with the Foot and Mouth Disease (FMD) virus. FMD is induced by a virus in the genus Apthovirus family Picornaviridae and is characterized by fever, hypersalivation, and vesicular lesions of the mouth and scrambled legs. This study used 12 cows with clinical symptoms of being infected with FMD virus in Sleman Regency, Yogyakrta Special Region. Blood sampling through the jugular vein was 6 ml and put into a Vacutainer tube with ethylene diamine tetra-acetic acid (EDTA) anticoagulants for later analysis of fibrinogen levels. The average fibrinogen value in the pre-drug administration phase was 380±130.38 mg/dL, the treatment phase was 633.33±136.63 mg/dL, and the cure phase was 566.67±136.63 mg/dL. Statistical analysis showed that fibrinogen levels in the pre-treatment phase, treatment phase, and recovery phase were significantly sig 0.02<(P0.05). The conclusions showed that there was a significant difference in fibrinogen levels between the pre-treatment phase, the treatment phase, and the recovery phase in FMD cows.

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DOI: https://doi.org/10.22146/ijvs.v3i2.83073