Fabrikasi Sensor Elektrokimia Berbasis Karbon dan Nanopartikel Perak (NPAg) Untuk Mendeteksi Acetaminophen

Abstract

Acetaminophen (paracetamol) is one of the most heavily used analgesic drugs especially for pain or pain relief. The excess of acetaminophen for the human body produces a bad effects, one of them is a liver disease. In this study, silver nanoparticle (NPAg) is synthesized using Turkevich methods to increase the conductivity or the rate of transfer electron in the carbon’s surface. So, the sensitivity from electrochemical sensors to acetaminophen can be enhanced. The stability test was done by three samples from Ag/AgCl reference electrodes, each of them is 10 – 30 mV, 0,94 – 35 mV, and 20 – 67 mV. Generally, the performing of Ag/AgCl refrence elecrodes can be concluded as fairly stable with voltage less than 100 mV. From the data acetaminophen sample test, the peak of oxidation happens on 0,2 – 0,4 mV session, and the current produced increased significantly. The results of characterization using SEM morphology in NPAg have a smaller pores because of the size of the partical is also big. While the characterization using FTIR produces four kinds of functional groups including C-O, C-H, NO2, and N-H functional groups.